LUXABENDAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H12FN3O5S
Molecular Weight	365.336
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC(=O)NC1=NC2=CC=C(OS(=O)(=O)C3=CC=C(F)C=C3)C=C2N1

InChI

InChIKey=ZVIDWFUBDDXAJA-UHFFFAOYSA-N

InChI=1S/C15H12FN3O5S/c1-23-15(20)19-14-17-12-7-4-10(8-13(12)18-14)24-25(21,22)11-5-2-9(16)3-6-11/h2-8H,1H3,(H2,17,18,19,20)

HIDE SMILES / InChI

Molecular Formula	C15H12FN3O5S
Molecular Weight	365.336
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/book/10.1007/978-1-4757-2085-3 | https://www.ncbi.nlm.nih.gov/pubmed/9673786 | https://www.ncbi.nlm.nih.gov/pubmed/2974592

Luxabendazole is a benzimidazole carbamate antihelmintic agent. In animal studies, it was effective against adult and immature stages of the major gastrointestinal nematodes, trematodes and cestodes.

Approval Year

PubMed

Title	Date	PubMed
Activity of luxabendazole against liver flukes, gastrointestinal roundworms, and lungworms in naturally infected sheep.	1988	2974592
Pharmacokinetics of luxabendazole after oral and intravenous administration to sheep.	1997 Nov	9361890
Pharmacokinetics of intravenous luxabendazole in rabbits: influence of the enterohepatic circulation.	1998 Jul	9673786

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:51:06 GMT 2023` Edited by `admin` on `Sat Dec 16 17:51:06 GMT 2023`
Record UNII	34S1S00GV3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LUXABENDAZOLE

Official Name

English

luxabendazole [INN]

Common Name

English

HOE-216V

Code

English

METHYL 5-HYDROXY-2-BENZIMIDAZOLECARBAMATE, P-FLUOROBENZENESULFONATE (ESTER)

Common Name

English

HOE 216V

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C250