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Details

Stereochemistry ACHIRAL
Molecular Formula C15H14O4
Molecular Weight 258.2693
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MENBUTONE

SMILES

COC1=CC=C(C(=O)CCC(O)=O)C2=CC=CC=C12

InChI

InChIKey=FHGJSJFIQNQBCK-UHFFFAOYSA-N
InChI=1S/C15H14O4/c1-19-14-8-6-11(13(16)7-9-15(17)18)10-4-2-3-5-12(10)14/h2-6,8H,7,9H2,1H3,(H,17,18)

HIDE SMILES / InChI

Molecular Formula C15H14O4
Molecular Weight 258.2693
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Menbutone is a choleretic compound which is used in veterinary medicine at a dose rate up to 10 mg/kg bw by parenteral (intravenous or intramuscular) route in bovine, ovine, caprine, porcine, and equine species. Menbutone stimulates the digestive tract by increasing excretion of bile, gastric acid, and pancreatic juices by two to five times baseline. It is marketed for veterinary use in Europe under several brand names.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Genabil

Approved Use

Menbutone is only to be administered to a small number of animals or individual animals which are not intended for immediate slaughter. The total daily intake should be at most 3.6 mg per person of 60 kg bw per day, resulting from the ADI of 0.06 mg/kg bw/day.

Launch Date

1996
PubMed

PubMed

TitleDatePubMed
Elimination and distribution of menbutone (Genabil) in rats.
1969
The choleretic effect of menbutone and clanobutin sodium in steers.
1982 May 1
Patents

Sample Use Guides

Menbutone is used in veterinary medicine at doses up to 10 mg/kg bw delivered by intravenous and intramuscular injection to bovine, ovine, caprine, porcine and equine species.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 15:48:31 GMT 2023
Edited
by admin
on Sat Dec 16 15:48:31 GMT 2023
Record UNII
341YM32546
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MENBUTONE
INN   MART.   MI  
INN  
Official Name English
PROPIONIC ACID, 3-(4-METHOXY-1-NAPHTHOYL)-
Common Name English
GENABILINE
Brand Name English
SC 1749 FREE ACID
Code English
SC-1749 FREE ACID
Code English
menbutone [INN]
Common Name English
NSC-53969
Code English
MENBUTONE [MI]
Common Name English
METHONAPHTHONE
Common Name English
MENBUTONE [MART.]
Common Name English
1-NAPHTHALENEBUTANOIC ACID, 4-METHOXY-.GAMMA.-OXO-
Common Name English
GENABILIN
Common Name English
GENABILIC ACID
Common Name English
3-(4-METHOXY-1-NAPHTHOYL)PROPIONIC ACID
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C1937
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
WHO-VATC QA05AX90
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
Code System Code Type Description
INN
2303
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
PUBCHEM
71818
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
CAS
3562-99-0
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
ECHA (EC/EINECS)
222-631-2
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
SMS_ID
100000081452
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID8046240
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
FDA UNII
341YM32546
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
ChEMBL
CHEMBL1972268
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
MESH
C011497
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
DRUG CENTRAL
3338
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
NCI_THESAURUS
C66087
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
NSC
53969
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
EVMPD
SUB08737MIG
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY
MERCK INDEX
m7172
Created by admin on Sat Dec 16 15:48:31 GMT 2023 , Edited by admin on Sat Dec 16 15:48:31 GMT 2023
PRIMARY Merck Index
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SALT/SOLVATE -> PARENT
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