NAPROXOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C14H16O2
Molecular Weight	216.2756
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=CC=C(C=C2C=C1)[C@H](C)CO

InChI

InChIKey=LTRANDSQVZFZDG-SNVBAGLBSA-N

InChI=1S/C14H16O2/c1-10(9-15)11-3-4-13-8-14(16-2)6-5-12(13)7-11/h3-8,10,15H,9H2,1-2H3/t10-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C14H16O2
Molecular Weight	216.2756
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:61022 | https://www.genome.jp/dbget-bin/www_bget?dr:D05121

Naproxol is an aromatic ether in which the substituents on oxygen are 6-[(2S)-1-hydroxypropan-2-yl]-2-naphthyl and methyl. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic.

Approval Year

PubMed

Title	Date	PubMed
A germination bioassay as a toxicological screening system for studying the effects of potential prodrugs of naproxen.	2015-06-05	26042491
Skin sensitizing properties of arylalcanoic acids and their analogues.	1979-09	509935

Patents

Sample Use Guides

In Vitro Use Guide

Both enantiomers of naproxen (6-methoxy-α-methyl-2-naphthaleneacetic acid) and naproxol (6-methoxy-β-2-naphthaleneethanol), and their racemic mixtures, inhibited the radicle growth of R. sativus at a concentration of 1mM

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:39:48 GMT 2025` Edited by `admin` on `Wed Apr 02 09:39:48 GMT 2025`
Record UNII	33S398GAY6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NAPROXOL

Official Name

English

NSC-758618

Preferred Name

English

(-)-(S)-6-METHOXY-.BETA.-METHYL-2-NAPHTHALENEETHANOL

Systematic Name

English

NAPROXOL [USAN]

Common Name

English

2-NAPHTHALENEETHANOL, 6-METHOXY-.BETA.-METHYL-, (S)-

Systematic Name

English

naproxol [INN]

Common Name

English

RS-4034

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257