FLUQUAZONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H10ClF3N2O
Molecular Weight	338.712
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC(F)(F)CN1C(=O)N=C(C2=CC=CC=C2)C3=C1C=CC(Cl)=C3

InChI

InChIKey=OAIZNWQBWDHNIH-UHFFFAOYSA-N

InChI=1S/C16H10ClF3N2O/c17-11-6-7-13-12(8-11)14(10-4-2-1-3-5-10)21-15(23)22(13)9-16(18,19)20/h1-8H,9H2

HIDE SMILES / InChI

Molecular Formula	C16H10ClF3N2O
Molecular Weight	338.712
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.genome.jp/dbget-bin/www_bget?drug+D04230 | Elks J., The Dictionary of Drugs: Chemical Data: Chemical Data, Structures, p. 571, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA571&lpg=PA571&dq=FLUQUAZONE&source=bl&ots=6JUhw5Zzuv&sig=ACfU3U3c2vdxhaksVBvfeUj7hD6fH9ac6A&hl=ru&sa=X&ved=2ahUKEwi94NvSms3jAhXJysQBHbWbBlw4FBDoATAGegQIBhAM#v=onepage&q=FLUQUAZONE&f=false

Fluquazone, a proquazone derivative, was studied as an anti-inflammatory agent. However, information about the further development of this compound is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
acute inflammatory response to antigenic stimulus 2 Target ID: GO:0002438 Sources: https://patents.google.com/patent/GB1307202A/en	Inhibitor 8504

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:09:44 GMT 2025` Edited by `admin` on `Mon Mar 31 18:09:44 GMT 2025`
Record UNII	31YX4A42L4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUQUAZONE

Official Name

English

EN-970

Preferred Name

English

FLUQUAZONE [USAN]

Common Name

English

fluquazone [INN]

Common Name

English

6-Chloro-4-phenyl-1-(2,2,2-trifluoroethyl)-2(1H)-quinazolinone

Systematic Name

English

2(1H)-QUINAZOLINONE, 6-CHLORO-4-PHENYL-1-(2,2,2-TRIFLUOROETHYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257