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Details

Stereochemistry ABSOLUTE
Molecular Formula C40H80NO8P
Molecular Weight 734.0389
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COLFOSCERIL PALMITATE

SMILES

CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

InChI

InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N
InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

HIDE SMILES / InChI

Molecular Formula C40H80NO8P
Molecular Weight 734.0389
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Colfosceril palmitate (dipalmitoylphosphatidylcholine) is a synthetic pulmonary surfactant, which is used in infants with respiratory distress syndrome it was approved in 1990, but nowadays it is under the state of canceled post-marketing. Colfosceril palmitate is reducing the tension and stabilizing the alveoli from collapsing.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
EXOSURF NEONATAL

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
319X2NFW0A
Record Status Validated (UNII)
Record Version