Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H10Br2ClNO2S |
| Molecular Weight | 463.571 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=O)OC1=C(Br)C=C(Cl)C=C1C(=S)NC2=CC=C(Br)C=C2
InChI
InChIKey=NRFGEDASJHBPPN-UHFFFAOYSA-N
InChI=1S/C15H10Br2ClNO2S/c1-8(20)21-14-12(6-10(18)7-13(14)17)15(22)19-11-4-2-9(16)3-5-11/h2-7H,1H3,(H,19,22)
| Molecular Formula | C15H10Br2ClNO2S |
| Molecular Weight | 463.571 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
BROTIANIDE is salicylanilide derivative used to treat fascioliasis in sheep. A dose of 7 mg/kg of brotianide shows 91-99% activity against 7-14 weeks old flukes; however, its activity against 6 weeks old flukes is weak (50-90%). It also possesses 85-90% activity against paramphistomes in sheep and cattle. The maximum tolerated dose of brotianide is 27 mg/kg in sheep.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:59:56 GMT 2023
by
admin
on
Fri Dec 15 15:59:56 GMT 2023
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| Record UNII |
30OGU6XH7S
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C250
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SUB05932MIG
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30OGU6XH7S
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C010873
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DTXSID00177807
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CHEMBL2106593
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245-505-9
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23233-88-7
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3034337
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2904
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100000085838
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C72595
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
