U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Dextranomer is a hydrophilic dextran polymer used as a biocompatible bulking agent, administered by submucosal injection. Dextranomer / hyaluronic acid treatment was associated with symptomatic improvement in adult fecal incontinence patients participating in a randomized, double-blind, study and non-comparative multinational study. Although there is limited discussion of the mechanism of action of dextranomer / hyaluronic acid in the literature, it is assumed that the dextranomer can expand the submucosal layer of the proximal anal canal, thereby increasing intestinal control. Dextranomer has been used as a 'cleansing agent' for various types of exudative wounds or ulcers, including stasis and pressure ulcers. Dextranomer appears to exert its effect due to capillary action, which absorbs wound exudate, as well as wound debris and microorganisms into the dextranomer beads or between the balls, thus removing such products from the surface of the wound. Dextranomer is an adjunct to the treatment of wounds or ulcers and does not have a direct effect on tissue repair in such ulcers, but, as in the case of other “cleansing” agents or methods, one can expect removal of residues (and possibly microorganisms) from the wound will promote natural healing.

Approval Year

PubMed

PubMed

TitleDatePubMed
Substance Class Polymer
Created
by admin
on Sat Dec 16 01:52:37 GMT 2023
Edited
by admin
on Sat Dec 16 01:52:37 GMT 2023
Record UNII
30KXI0TVD3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEXTRANOMER
INN   MI   VANDF   WHO-DD  
INN  
Official Name English
COMPONENT OF SOLESTA
Brand Name English
DEXTRANOMER [MI]
Common Name English
DEXTRANOMER [VANDF]
Common Name English
DEBRISAN
Common Name English
DEXTRAN 2,3-DIHYDROXYPROPYL 2-HYDROXY-1,3-PROPANEDIYL ETHER
Common Name English
DEBRISORB
Brand Name English
DEXTRANOMER [JAN]
Common Name English
SOLESTA COMPONENT
Brand Name English
DEXTRANOMER [EP MONOGRAPH]
Common Name English
dextranomer [INN]
Common Name English
Dextranomer [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-ATC D03AX02
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
WHO-VATC QD03AX02
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
Code System Code Type Description
SMS_ID
100000087785
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
MESH
C013471
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
FDA UNII
30KXI0TVD3
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
MERCK INDEX
m4222
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY Merck Index
INN
3822
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
RXCUI
22708
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY RxNorm
DRUG BANK
DB13560
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
EVMPD
SUB01643MIG
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
CAS
56087-11-7
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
NCI_THESAURUS
C166616
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
WIKIPEDIA
Dextranomer
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108201
Created by admin on Sat Dec 16 01:52:38 GMT 2023 , Edited by admin on Sat Dec 16 01:52:38 GMT 2023
PRIMARY
Display Structure of DEXTRANOMER
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CROSSLINKING CROSSLINKER CROSSLINKER EPICHLOROHYDRIN 08OOR508C0