Vobramitamab Duocarmazine

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:02:30 GMT 2023` Edited by `admin` on `Sat Dec 16 14:02:30 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	2ZK3D69DQJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Vobramitamab Duocarmazine

Official Name

English

AEX4089DC1

Common Name

English

MGC-018

Code

English

MGC018

Code

English

vobramitamab duocarmazine [INN]

Common Name

English

MGC 018 [WHO-DD]

Common Name

English

Immunoglobulin G1 [de-447-lysine], anti-(human B7 homolog 3 protein)(human-Mus musculus monoclonal PRCA157 γ1-chain), disulfide with human-Mus musculus monoclonal PRCA157 κ-chain, dimer, thioether with N-[[2-[2-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)etho

Common Name

English

ANTI-B7H3 ANTIBODY-DRUG CONJUGATE MGC018

Common Name

English

VOBRAMITAMAB DUOCARMAZINE [USAN]

Common Name

English

Code System Code Type Description

USAN

KL-246

Created by admin on Sat Dec 16 14:02:30 GMT 2023 , Edited by admin on Sat Dec 16 14:02:30 GMT 2023

PRIMARY

CAS

2490556-51-7

Created by admin on Sat Dec 16 14:02:30 GMT 2023 , Edited by admin on Sat Dec 16 14:02:30 GMT 2023

PRIMARY

INN

12056

Created by admin on Sat Dec 16 14:02:30 GMT 2023 , Edited by admin on Sat Dec 16 14:02:30 GMT 2023

PRIMARY

FDA UNII

2ZK3D69DQJ

Created by admin on Sat Dec 16 14:02:30 GMT 2023 , Edited by admin on Sat Dec 16 14:02:30 GMT 2023

PRIMARY

NCI_THESAURUS

C159495

Created by admin on Sat Dec 16 14:02:30 GMT 2023 , Edited by admin on Sat Dec 16 14:02:30 GMT 2023

PRIMARY

NCIT

From	To
1_22	1_96
1_144	1_200
1_220	3_215
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_220	4_215
2_261	2_321
2_367	2_425
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					961Y201EWR

TARGET->CONJUGATED TOXIN

Amount:

Related Record Type Details


					LU3A693LFA

DUBA

METABOLITE ACTIVE -> PARENT

Amount:

Related Record Type Details


					2ZK3D69DQJ

Vobramitamab Duocarmazine

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL