Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C64H93N11O16 |
| Molecular Weight | 1272.4873 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(O)=O)NC(=O)CCCCN)C(=O)N3CCC[C@H]3C(=O)N([C@@H](CC(C)C)C(O)=O)C(=O)CCCCNC(=O)[C@@H]4CCCN4C(=O)[C@H](N)CC5=CC=CC=C5
InChI
InChIKey=VKIPOMGKUAJAEY-GEPLSBMPSA-N
InChI=1S/C64H93N11O16/c1-5-40(4)55(71-59(85)48-24-17-33-73(48)61(87)44(28-29-53(78)79)69-56(82)45(37-42-21-10-7-11-22-42)70-57(83)46(38-54(80)81)68-51(76)26-12-14-30-65)63(89)74-34-18-25-49(74)62(88)75(50(64(90)91)35-39(2)3)52(77)27-13-15-31-67-58(84)47-23-16-32-72(47)60(86)43(66)36-41-19-8-6-9-20-41/h6-11,19-22,39-40,43-50,55H,5,12-18,23-38,65-66H2,1-4H3,(H,67,84)(H,68,76)(H,69,82)(H,70,83)(H,71,85)(H,78,79)(H,80,81)(H,90,91)/t40-,43+,44-,45-,46-,47-,48-,49-,50-,55-/m0/s1
| Molecular Formula | C64H93N11O16 |
| Molecular Weight | 1272.4873 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Urban particulate matter activates Akt in human lung cells. | 2012-01 |
|
| Molecular modeling: a search for a calpain inhibitor as a new treatment for cataractogenesis. | 2011-11-10 |
|
| 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) induces degradation of adherens junction proteins and inhibits beta-catenin-dependent transcription in liver epithelial cells. | 2009-06-16 |
|
| Endothelial gap junctions are down-regulated by arsenic trioxide. | 2007-08-13 |
|
| Regulation of adipocyte lipolysis by degradation of the perilipin protein: nelfinavir enhances lysosome-mediated perilipin proteolysis. | 2007-07-27 |
|
| Defective hepatocyte aquaporin-8 expression and reduced canalicular membrane water permeability in estrogen-induced cholestasis. | 2007-03 |
|
| Activation and enzymatic characterization of recombinant human kallikrein 8. | 2006-06 |
|
| Transforming growth factor-beta1 inhibits all-trans retinoic acid-induced apoptosis. | 2006-05 |
|
| Proteasomal degradation of caspase-6 in 17beta-estradiol-treated neurons. | 2004-05 |
|
| Inhibition of proteolysis by a cyclooxygenase inhibitor, indomethacin. | 2000-11 |
|
| Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. | 1997-05-01 |
|
| Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation. | 1996-12 |
|
| Efficacy of serine protease inhibitors against Cryptosporidium parvum infection in a bovine fallopian tube epithelial cell culture system. | 1996-08 |
|
| Antiviral effect of oryzacystatin, a proteinase inhibitor in rice, against herpes simplex virus type 1 in vitro and in vivo. | 1995-04 |
|
| Peptide aldehydes as inhibitors of HIV protease. | 1993-03-22 |
|
| Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease. | 1991-08-27 |
|
| Inhibition of the growth of human coronavirus 229E by leupeptin. | 1985-02 |
|
| Drug-induced lysosomal changes and nephrotoxicity in rats. | 1978-11 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:18:31 GMT 2025
by
admin
on
Mon Mar 31 23:18:31 GMT 2025
|
| Record UNII |
2Y77S7IT1P
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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72941757
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2Y77S7IT1P
Created by
admin on Mon Mar 31 23:18:31 GMT 2025 , Edited by admin on Mon Mar 31 23:18:31 GMT 2025
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