U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C18H17N3O2
Molecular Weight 307.3465
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANITRAZAFEN

SMILES

COC1=CC=C(C=C1)C2=NN=C(C)N=C2C3=CC=C(OC)C=C3

InChI

InChIKey=HDNJXZZJFPCFHG-UHFFFAOYSA-N
InChI=1S/C18H17N3O2/c1-12-19-17(13-4-8-15(22-2)9-5-13)18(21-20-12)14-6-10-16(23-3)11-7-14/h4-11H,1-3H3

HIDE SMILES / InChI

Molecular Formula C18H17N3O2
Molecular Weight 307.3465
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Anitrazafen is a topically effective anti-inflammatory agent. Аpplied topically to guinea-pigs, anitrazafen is a potent anti-inflammatory agent capable both of delaying the onset of and reversing, developing erythema induced by U.V. light. Anitrazafen, following oral administration to rats, showed only slight to moderate activity in the carrageenan-induced paw oedema and adjuvant-induced arthritis tests

Approval Year

Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 15:36:51 GMT 2023
Edited
by admin
on Fri Dec 15 15:36:51 GMT 2023
Record UNII
2Y065P7MYR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANITRAZAFEN
INN   USAN  
USAN   INN  
Official Name English
ANITRAZAFEN [USAN]
Common Name English
5,6-BIS(P-METHOXYPHENYL)-3-METHYL-AS-TRIAZINE
Common Name English
anitrazafen [INN]
Common Name English
NSC-336394
Code English
LY 122512
Code English
LY-122512
Code English
1,2,4-TRIAZINE, 5,6-BIS(4-METHOXYPHENYL)-3-METHYL-
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C308
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
Code System Code Type Description
WIKIPEDIA
ANITRAZAFEN
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
FDA UNII
2Y065P7MYR
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
NSC
336394
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
CAS
63119-27-7
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
INN
4748
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
SMS_ID
100000086949
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
PUBCHEM
44410
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
MESH
C029087
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
ChEMBL
CHEMBL2105947
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
NCI_THESAURUS
C81668
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
EVMPD
SUB05522MIG
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
EPA CompTox
DTXSID50212454
Created by admin on Fri Dec 15 15:36:51 GMT 2023 , Edited by admin on Fri Dec 15 15:36:51 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY