Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H8N4O4 |
| Molecular Weight | 224.1735 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][N+](=O)C1=CC=C(O1)\C=N\N2CCNC2=O
InChI
InChIKey=VSVAVMVWTLLTCH-BJMVGYQFSA-N
InChI=1S/C8H8N4O4/c13-8-9-3-4-11(8)10-5-6-1-2-7(16-6)12(14)15/h1-2,5H,3-4H2,(H,9,13)/b10-5+
| Molecular Formula | C8H8N4O4 |
| Molecular Weight | 224.1735 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Nifuradene (NF-246), a chemotherapeutic
nitrofuran, was first synthesized and reported
in 1956. Nifuradene, a 5-Nitorofuran derivative, is an antibacterial drug. Early in vitro testing
found it an effective chemotherapeutic agent
against most of the common urinary pathogens. Subsequent in vivo studies found that this compound is well absorbed after oral administration
in both animals and humans. Nifuradene was used for the treatment of urinary tract infections. The over-all cure rate was found
to be best at doses exceeding 600 mg a day.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:32:35 GMT 2025
by
admin
on
Mon Mar 31 21:32:35 GMT 2025
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| Record UNII |
2VX65207DR
|
| Record Status |
Validated (UNII)
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| Record Version |
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Official Name | English | ||
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Preferred Name | English | ||
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Code | English | ||
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C28394
Created by
admin on Mon Mar 31 21:32:35 GMT 2025 , Edited by admin on Mon Mar 31 21:32:35 GMT 2025
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| Code System | Code | Type | Description | ||
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CHEMBL265442
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DTXSID2020973
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m369
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PRIMARY | Merck Index | ||
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2VX65207DR
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6470
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SUB09258MIG
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3795
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555-84-0
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9568055
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100000083848
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C84015
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2051
Created by
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
