Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C26H44O2 |
| Molecular Weight | 388.6264 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCC1(CCCCC)CC2=C(C(O)=C(C=C2O1)C(C)(C)C)C(C)(C)C
InChI
InChIKey=AGURKSYKTJQPNA-UHFFFAOYSA-N
InChI=1S/C26H44O2/c1-9-11-13-15-26(16-14-12-10-2)18-19-21(28-26)17-20(24(3,4)5)23(27)22(19)25(6,7)8/h17,27H,9-16,18H2,1-8H3
| Molecular Formula | C26H44O2 |
| Molecular Weight | 388.6264 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Macrophage scavenger receptor (SR-A I/II) deficiency reduced diet-induced atherosclerosis in C57BL/6J mice. | 2001 |
|
| Effect of BO-653 and probucol on c-MYC and PDGF-A messenger RNA of the iliac artery after balloon denudation in cholesterol-fed rabbits. | 2002 Apr |
|
| Antioxidant action of 2,2,4,6-tetra-substituted 2,3-dihydro-5-hydroxybenzofuran against lipid peroxidation: effects of substituents and side chain. | 2002 Nov |
|
| Design and synthesis of 4,6-di-tert-butyl-2,3-dihydro-5-benzofuranols as a novel series of antiatherogenic antioxidants. | 2003 Jul 3 |
|
| BO-653. Chugai. | 2003 Mar |
|
| Inhibition of plasma lipid peroxidation by anti-atherogenic antioxidant BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran. | 2004 Sep 1 |
|
| Inhibition of lipoprotein lipid oxidation. | 2005 |
|
| The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion I: enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs. | 2005 Aug |
|
| Characterization of the oxidation products of BO-653 formed during peroxyl radical-mediated oxidation of human plasma. | 2005 Jan 1 |
|
| Lipid peroxidation induced by carbon tetrachloride and its inhibition by antioxidant as evaluated by an oxidative stress marker, HODE. | 2005 Oct 1 |
|
| Lipid peroxidation in mice fed a choline-deficient diet as evaluated by total hydroxyoctadecadienoic acid. | 2006 Mar |
|
| Protective effect of vitamin E supplements on experimental atherosclerosis is modest and depends on preexisting vitamin E deficiency. | 2006 Sep 1 |
|
| Cytotoxic effects of various stressors on PC12 cells: involvement of oxidative stress and effect of antioxidants. | 2007 Jan |
|
| Evaluation of lipophilic antioxidant efficacy in vivo by the biomarkers hydroxyoctadecadienoic acid and isoprostane. | 2007 May |
|
| Antioxidant effects of 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran and alpha-tocopherol in hyperlipidemic mice as evaluated by hydroxyoctadecadienoic acid and 7-hydroxycholesterol. | 2007 Oct 1 |
|
| Antioxidant capacity of BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran, and uric acid as evaluated by ORAC method and inhibition of lipid peroxidation. | 2008 Apr 1 |
|
| Design, synthesis, and action of antiatherogenic antioxidants. | 2010 |
|
| Synthetic lipophilic antioxidant BO-653 suppresses HCV replication. | 2013 Feb |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:22:43 GMT 2023
by
admin
on
Fri Dec 15 16:22:43 GMT 2023
|
| Record UNII |
2VSP9T5LRX
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2VSP9T5LRX
Created by
admin on Fri Dec 15 16:22:43 GMT 2023 , Edited by admin on Fri Dec 15 16:22:43 GMT 2023
|
PRIMARY | |||
|
DTXSID20166253
Created by
admin on Fri Dec 15 16:22:43 GMT 2023 , Edited by admin on Fri Dec 15 16:22:43 GMT 2023
|
PRIMARY | |||
|
9800472
Created by
admin on Fri Dec 15 16:22:43 GMT 2023 , Edited by admin on Fri Dec 15 16:22:43 GMT 2023
|
PRIMARY | |||
|
157360-23-1
Created by
admin on Fri Dec 15 16:22:43 GMT 2023 , Edited by admin on Fri Dec 15 16:22:43 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
