Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C14H22N2OS |
| Molecular Weight | 266.402 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O
InChI
InChIKey=YCNCXQNUXCHRRX-ZHPDPMBESA-N
InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1
| Molecular Formula | C14H22N2OS |
| Molecular Weight | 266.402 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221). | 2010 Jun 10 |
|
| Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1. | 2011 Sep 8 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:33:33 GMT 2023
by
admin
on
Sat Dec 16 08:33:33 GMT 2023
|
| Record UNII |
2T929W7AG8
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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948044-21-1
Created by
admin on Sat Dec 16 08:33:33 GMT 2023 , Edited by admin on Sat Dec 16 08:33:33 GMT 2023
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SUPERSEDED | |||
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2T929W7AG8
Created by
admin on Sat Dec 16 08:33:33 GMT 2023 , Edited by admin on Sat Dec 16 08:33:33 GMT 2023
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135565424
Created by
admin on Sat Dec 16 08:33:33 GMT 2023 , Edited by admin on Sat Dec 16 08:33:33 GMT 2023
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PRIMARY | |||
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1095565-81-3
Created by
admin on Sat Dec 16 08:33:33 GMT 2023 , Edited by admin on Sat Dec 16 08:33:33 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
