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Details

Stereochemistry RACEMIC
Molecular Formula C15H18Cl2N4O3
Molecular Weight 373.234
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIDAZOLOL

SMILES

OC(CNCCNC1=C(Cl)C(=O)NN=C1)COC2=C(Cl)C=CC=C2

InChI

InChIKey=UUWABVCZFXKHSU-UHFFFAOYSA-N
InChI=1S/C15H18Cl2N4O3/c16-11-3-1-2-4-13(11)24-9-10(22)7-18-5-6-19-12-8-20-21-15(23)14(12)17/h1-4,8,10,18,22H,5-7,9H2,(H2,19,21,23)

HIDE SMILES / InChI

Molecular Formula C15H18Cl2N4O3
Molecular Weight 373.234
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Ridazolol is a cardioselective and vasodilating beta-adrenergic receptor antagonist. It also has moderate alpha-adrenolytic activity (the presence of a heterogeneous population of postjunctional alpha adrenoceptors has been suggested). Ridazolol was investigated for use in arrhythmias and ischaemic heart disorders. In patients with confirmed coronary artery disease and reproducible ST-segment depression, blood pressure and heart rate under exercise were significantly reduced for 5 hours, and improvement of ST-segment depression lasted 1 hour. Ridazolol is well tolerated. This drug is not currently used.

Originator

Approval Year

Substance Class Chemical
Record UNII
2R4QO1868Y
Record Status Validated (UNII)
Record Version