Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H19BrN6O |
| Molecular Weight | 463.33 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=C2C(=CC(=NC2=NC=N1)C3=CC=C(N=C3)N4CCOCC4)C5=CC=CC(Br)=C5
InChI
InChIKey=RQCXKDWOCUJWQZ-UHFFFAOYSA-N
InChI=1S/C22H19BrN6O/c23-16-3-1-2-14(10-16)17-11-18(28-22-20(17)21(24)26-13-27-22)15-4-5-19(25-12-15)29-6-8-30-9-7-29/h1-5,10-13H,6-9H2,(H2,24,26,27,28)
| Molecular Formula | C22H19BrN6O |
| Molecular Weight | 463.33 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Inhibition of Antiapoptotic BCL-XL, BCL-2, and MCL-1 Proteins by Small Molecule Mimetics. | 2010-08-12 |
|
| 4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors. | 2007-02-15 |
|
| 5-(3-Bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine: structure-activity relationships of 7-substituted heteroaryl analogs as non-nucleoside adenosine kinase inhibitors. | 2005-06-01 |
|
| Pharmacological characterization of the chronic constriction injury model of neuropathic pain. | 2004-05-03 |
|
| Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor.. | 2001-06-21 |
|
| ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse. | 2000-12 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:25:43 GMT 2025
by
admin
on
Mon Mar 31 18:25:43 GMT 2025
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| Record UNII |
2P206WS5B3
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| Record Status |
Validated (UNII)
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| Record Version |
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214697-26-4
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DTXSID901017168
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