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Details

Stereochemistry ACHIRAL
Molecular Formula C14H20N2O
Molecular Weight 232.3214
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORFENTANYL

SMILES

CCC(=O)N(C1CCNCC1)C2=CC=CC=C2

InChI

InChIKey=PMCBDBWCQQBSRJ-UHFFFAOYSA-N
InChI=1S/C14H20N2O/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13/h3-7,13,15H,2,8-11H2,1H3

HIDE SMILES / InChI
Molecular Formula C14H20N2O
Molecular Weight 232.3214
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14607008

Norfentanyl is a major urinary metabolite of a potent, synthetic narcotic analgesic fentanyl.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Development of an enzyme-linked immunosorbent assay for fentanyl and applications of fentanyl antibody-coated nanoparticles for sample preparation.
2006 Jun 16
Development of novel enkephalin analogues that have enhanced opioid activities at both mu and delta opioid receptors.
2007 Nov 1
Patents

Patents

FR1344366
2

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 04:54:48 GMT 2023
Edited
by admin
on Sat Dec 16 04:54:48 GMT 2023
Record UNII
2MK6D8JV6J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORFENTANYL
Common Name English
PROPANAMIDE, N-PHENYL-N-4-PIPERIDINYL-
Systematic Name English
N-PHENYL-N-(PIPERIDIN-4-YL)PROPANAMIDE
Systematic Name English
N-PHENYL-N-(PIPERIDIN-4-YL)PROPIONAMIDE
Common Name English
FENTANYL IMPURITY B [EP IMPURITY]
Common Name English
FENTANYL CITRATE IMPURITY B [EP IMPURITY]
Common Name English
FENTANYL RELATED COMPOUND C [USP IMPURITY]
Common Name English
N-(PIPERIDIN-4-YL)-N-PHENYLPROPIONAMIDE
Systematic Name English
NSC-89293
Code English
4-(N-PROPIONYLANILINE)PIPERIDINE
Common Name English
4-(N-PROPIONANILIDO)PIPERIDINE
Common Name English
N-PHENYL-N-(4-PIPERIDINYL)PROPANAMIDE
Systematic Name English
N-PHENYL-N-4-PIPERIDINYLPROPIONAMIDE
Systematic Name English
FENTANYL RELATED COMPOUND C
USP  
Common Name English
Classification Tree Code System Code
DEA NO. 8366
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
Code System Code Type Description
CHEBI
62685
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
PUBCHEM
259381
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
NSC
89293
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
ECHA (EC/EINECS)
216-543-3
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
FDA UNII
2MK6D8JV6J
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
EVMPD
SUB34914
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
SMS_ID
100000128157
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
CAS
1609-66-1
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
EPA CompTox
DTXSID2057657
Created by admin on Sat Dec 16 04:54:49 GMT 2023 , Edited by admin on Sat Dec 16 04:54:49 GMT 2023
PRIMARY
Related Record Type Details
Structure of NORFENTANYL-D5 (PHENYL-D5) HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of FENTANYL
PARENT -> METABOLITE
Structure of .ALPHA.-METHYLFENTANYL
PARENT -> METABOLITE INACTIVE
MAJOR
Structure of FENTANYL
PARENT -> METABOLITE INACTIVE
MAJOR
PLASMA
Structure of .OMEGA.-1 HYDROXYPROPIONYL NOR-FENTANYL
METABOLITE -> PARENT
Stereochemistry unknown for metabolite. Excreted in rat urine of metabolite .omega.-1 Hydroxypropionyl nor-fentanyl (%):Time after the injection(0?24 h) 2.2+-0.8, (24?48 h) 3.2+-0.6, (48?72 h) 1.9+-0.4, limit of detection- (72?96 h)
Related Record Type Details
Structure of FENTANYL
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of FENTANYL CITRATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of NORFENTANYL
ACTIVE MOIETY
NIH
NCATS
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