Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H26F3N3O3S |
| Molecular Weight | 481.531 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)C[C@H](N[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)S(C)(=O)=O)C(F)(F)F)C(=O)NCC#N
InChI
InChIKey=VYFDSJLOCIGIKP-SFTDATJTSA-N
InChI=1S/C23H26F3N3O3S/c1-15(2)14-20(22(30)28-13-12-27)29-21(23(24,25)26)18-6-4-16(5-7-18)17-8-10-19(11-9-17)33(3,31)32/h4-11,15,20-21,29H,13-14H2,1-3H3,(H,28,30)/t20-,21-/m0/s1
| Molecular Formula | C23H26F3N3O3S |
| Molecular Weight | 481.531 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools. | 2009-09 |
|
| Identification of a potent and selective non-basic cathepsin K inhibitor. | 2006-04-01 |
|
| Recent developments in cathepsin K inhibitor design. | 2005-09 |
|
| Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate. | 2001-10 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:01:53 GMT 2025
by
admin
on
Mon Mar 31 22:01:53 GMT 2025
|
| Record UNII |
29250PP3ON
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
29250PP3ON
Created by
admin on Mon Mar 31 22:01:53 GMT 2025 , Edited by admin on Mon Mar 31 22:01:53 GMT 2025
|
PRIMARY | |||
|
9913088
Created by
admin on Mon Mar 31 22:01:53 GMT 2025 , Edited by admin on Mon Mar 31 22:01:53 GMT 2025
|
PRIMARY | |||
|
603139-12-4
Created by
admin on Mon Mar 31 22:01:53 GMT 2025 , Edited by admin on Mon Mar 31 22:01:53 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
