Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H26F3N3O3S |
| Molecular Weight | 481.531 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)C[C@H](N[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)S(C)(=O)=O)C(F)(F)F)C(=O)NCC#N
InChI
InChIKey=VYFDSJLOCIGIKP-SFTDATJTSA-N
InChI=1S/C23H26F3N3O3S/c1-15(2)14-20(22(30)28-13-12-27)29-21(23(24,25)26)18-6-4-16(5-7-18)17-8-10-19(11-9-17)33(3,31)32/h4-11,15,20-21,29H,13-14H2,1-3H3,(H,28,30)/t20-,21-/m0/s1
| Molecular Formula | C23H26F3N3O3S |
| Molecular Weight | 481.531 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Potent and selective inhibition of human cathepsin K leads to inhibition of bone resorption in vivo in a nonhuman primate. | 2001 Oct |
|
| Recent developments in cathepsin K inhibitor design. | 2005 Sep |
|
| Identification of a potent and selective non-basic cathepsin K inhibitor. | 2006 Apr 1 |
|
| Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools. | 2009 Sep |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:22:06 GMT 2023
by
admin
on
Sat Dec 16 08:22:06 GMT 2023
|
| Record UNII |
29250PP3ON
|
| Record Status |
Validated (UNII)
|
| Record Version |
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29250PP3ON
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9913088
Created by
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603139-12-4
Created by
admin on Sat Dec 16 08:22:06 GMT 2023 , Edited by admin on Sat Dec 16 08:22:06 GMT 2023
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