U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C6H12O5
Molecular Weight 164.1567
Optical Activity ( - )
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Elfucose

SMILES

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O

InChI

InChIKey=PNNNRSAQSRJVSB-KCDKBNATSA-N
InChI=1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1

HIDE SMILES / InChI
Molecular Formula C6H12O5
Molecular Weight 164.1567
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

2014
503
PubMed

PubMed

TitleDatePubMed
Molecular cloning and characterization of a novel human beta1,3-glucosyltransferase, which is localized at the endoplasmic reticulum and glucosylates O-linked fucosylglycan on thrombospondin type 1 repeat domain.
2006-12
Substrate discrimination by the human GTP fucose pyrophosphorylase.
2005-08-16
Human symbionts use a host-like pathway for surface fucosylation.
2005-03-18
Polysaccharides of Ganoderma lucidum alter cell immunophenotypic expression and enhance CD56+ NK-cell cytotoxicity in cord blood.
2004-11-01
The oligosaccharidic content of the glycoconjugates of the prepubertal descended and undescended testis: lectin histochemical study.
2004-10-16
Pharmacology of skin aging. Stimulation of glycosaminoglycan biosynthesis by L-fucose and fucose-rich polysaccharides, effect of in vitro aging of fibroblasts.
2004-04
[Role of cytokines in the metabolism of the extracellular matrix carbohydrate-protein components in patients of various ages with gastroduodenal ulcer].
2001-11-06
Evaluation of glycoproteins as prognosticators in head and neck malignancy.
2001-10-23
GDP-4-keto-6-deoxy-D-mannose epimerase/reductase from Escherichia coli, a key enzyme in the biosynthesis of GDP-L-fucose, displays the structural characteristics of the RED protein homology superfamily.
1998-11-15
The metabolism of 6-deoxyhexoses in bacterial and animal cells.
1998-11
Human epidermal Langerhans cells express the mannose-fucose binding receptor.
1998-11
Sialyl Lewis(x) epitopes do not occur on acute phase proteins in mice: relationship to the absence of alpha3-fucosyltransferase in the liver.
1998-04
[Adhesins of Acinetobacter strains].
1998
Effect of L-fucose and D-glucose concentration on L-fucoprotein metabolism in human Hep G2 cells and changes in fucosyltransferase and alpha-L-fucosidase activity in liver of diabetic rats.
1997-04-17
O-linked L-fucose is present in Desmodus rotundus salivary plasminogen activator.
1996-03-29
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma.
1995-03-01
Monoclonal antibody FW6 defines an epitope on alpha 3/4-monofucosylated polylactosaminoglycans expressed by fetal and colon carcinoma-associated mucins.
1993-09-15
A monoclonal IgM kappa from a blood group B individual with specificity for alpha-galactosyl epitopes on partially hydrolyzed blood group B substance.
1993-05-07
Fucosyltransferases: differential plasma and tissue alterations in hepatocellular carcinoma and cirrhosis.
1991-04
Lectin cytochemical evaluation of somatosensory neurons and their peripheral and central processes in rat and man.
1986
Studies on the plasma membrane of normal and psoriatic keratinocytes. 6. Cell surface and shed glycoproteins.
1983-01
Patents

Patents

05438130
1
JP2000125857A
1
JP2003231694A
5
JP2008120707A
1
JP5327642B2
1
JPH00690765A
1
JPH07115968A
1
JPH07184647A
1
JPH08242876A
1
JPH1135591A
1
JPH1160593A
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:34:34 GMT 2025
Edited
by admin
on Mon Mar 31 18:34:34 GMT 2025
Record UNII
28RYY2IV3F
Record Status FAILED
Record Version
  • Download
Name Type Language
Elfucose
USAN   INN  
Official Name English
FUCOSE
INCI  
INCI  
Preferred Name English
L-FUCOSE
MI   USP-RS  
Common Name English
6-deoxy-L-galactose
Systematic Name English
elfucose [INN]
Common Name English
ELFUCOSE [USAN]
Common Name English
(-)-FUCOSE
Common Name English
AVTX-803
Code English
DEOXYGALACTOSE-CERECOR
Common Name English
FUCOSE, L-
Common Name English
6-deoxy-L-galactopyranose
Common Name English
L-FUCOSE [MI]
Common Name English
FUCOSE-CERECOR
Common Name English
L-(-)-FUCOSE
Common Name English
L-FUCOSE [USP-RS]
Common Name English
NSC-1219
Code English
L-GALACTOMETHYLOSE
Common Name English
L-fucopyranose
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 667018
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
NCI_THESAURUS C68479
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
FDA ORPHAN DRUG 753120
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
Code System Code Type Description
CHEBI
18287
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
CHEBI
33984
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
USAN
JK-273
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
CAS
87-96-7
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
ALTERNATIVE
RXCUI
2466731
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-785-4
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
ALTERNATIVE
DAILYMED
28RYY2IV3F
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
EPA CompTox
DTXSID50883845
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
CAS
2438-80-4
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
INN
12611
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
FDA UNII
28RYY2IV3F
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
NSC
1219
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
NCI_THESAURUS
C68481
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY NCIT
DRUG BANK
DB15236
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
MESH
D005643
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
PUBCHEM
3034656
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
SMS_ID
300000041011
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
MERCK INDEX
m5578
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY Merck Index
RS_ITEM_NUM
1286606
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
WIKIPEDIA
FUCOSE
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
ECHA (EC/EINECS)
219-452-7
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
CHEBI
2181
Created by admin on Mon Mar 31 18:34:34 GMT 2025 , Edited by admin on Mon Mar 31 18:34:34 GMT 2025
PRIMARY
Related Record Type Details
Structure of Elfucose
ACTIVE MOIETY
Fucose replacements
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966