DIISOPROMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H29N
Molecular Weight	295.4617
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIISOPROMINE

Structure Search

SMILES

CC(C)N(CCC(C1=CC=CC=C1)C2=CC=CC=C2)C(C)C

InChI

InChIKey=YBJKOPHEJOMRMN-UHFFFAOYSA-N

InChI=1S/C21H29N/c1-17(2)22(18(3)4)16-15-21(19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-14,17-18,21H,15-16H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C21H29N
Molecular Weight	295.4617
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://home.intekom.com/pharm/janssen/agofell.html | https://www.ncbi.nlm.nih.gov/pubmed/14124235

Diisopromine, a spasmolytic and a choleretic, in combination with sorbitol was marketed under the brand name Agofell. Agofell is prescribed for the biliary stasis and biliary insufficiency, hypotonia of the gall bladder, spasm of the biliary duct and of the sphincter of Oddi, cholecystitis, cholelithiasis, post cholecystotomy syndrome.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[TREATMENT OF FUNCTIONAL DISORDERS OF THE EXTRAHEPATIC BILIARY SYSTEM WITH AGOFELL].	1964 Jan 31	14124235

Sample Use Guides

In Vivo Use Guide

One 5 mL measure of syrup (Diisopromine hydrochloride and sorbitol) to be taken 15 minutes before the principal meals.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:17:37 GMT 2023` Edited by `admin` on `Fri Dec 15 16:17:37 GMT 2023`
Record UNII	2825S6AW9U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIISOPROMINE

Official Name

English

R-253

Code

English

BENZENEPROPANAMINE, N,N-BIS(1-METHYLETHYL)-.GAMMA.-PHENYL-

Systematic Name

English

DIISOPROMINE [MI]

Common Name

English

N,N-DIISOPROPYL-3,3-DIPHENYLPROPYLAMINE

Systematic Name

English

diisopromine [INN]

Common Name

English

Diisopromine [WHO-DD]

Common Name

English

DISOPROMINE

Common Name

English

PROPYLAMINE, N,N-DIISOPROPYL-3,3-DIPHENYL-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

WHO-VATC

QA03AX02

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

WHO-ATC

A03AX02

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

Code System Code Type Description

NCI_THESAURUS

C80978

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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EVMPD

SUB07143MIG

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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MERCK INDEX

m694

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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Merck Index

SMS_ID

100000082608

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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ECHA (EC/EINECS)

227-752-4

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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RXCUI

236206

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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RxNorm

WIKIPEDIA

Diisopromine

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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EPA CompTox

DTXSID60208343

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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PUBCHEM

22262

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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INN

989

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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DRUG BANK

DB13476

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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ChEMBL

CHEMBL2110849

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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DRUG CENTRAL

892

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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FDA UNII

2825S6AW9U

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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CAS

5966-41-6

Created by admin on Fri Dec 15 16:17:37 GMT 2023 , Edited by admin on Fri Dec 15 16:17:37 GMT 2023

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Related Record Type Details


					9E8EN393AL

DIISOPROMINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					2825S6AW9U

ACTIVE MOIETY