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ALGLUCERASE
27T56C7KK0
US Previously Marketed
First approved in 1991
General
Record Details
Names
10
Classification
7
Identifiers
13
Subunits
1
Active Moiety
1
Characteristic Attributes
3
ALGLUCERASE
27T56C7KK0
US Previously Marketed
First approved in 1991
General
Approval Year
1991
113
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Origin
HUMAN
Sequence Type
COMPLETE
Record UNII
27T56C7KK0
Record Status
Validated (UNII)
Record Version
19
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Names
10
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entries
Name
Type
Language
Name
Type
Language
ALGLUCERASE
Official Name
English
Alglucerase [WHO-DD]
Common Name
English
ALGLUCERASE [MI]
Common Name
English
ALGLUCERASE [USAN]
Common Name
English
ALGLUCERASE [VANDF]
Common Name
English
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Classification
7
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Enzymes
VATC
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
alglucerase
WHO-VATC
QA16AB01
Established Pharmacologic Class
Established Pharmacologic Class
[EPC]
Hydrolytic Lysosomal Glucocerebroside-specific Enzyme
[EPC]
NDF-RT
N0000175820
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Enzyme Replacement or Supplement Agent
NCI_THESAURUS
C29726
Designated/Approved
ORPHAN DRUG
Designated/Approved
For replacement therapy in patients with Gaucher's disease type I.
FDA ORPHAN DRUG
5585
Designated
ORPHAN DRUG
Designated
Replacement therapy in patients with Type II and III Gaucher's disease.
FDA ORPHAN DRUG
91095
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Identifiers
13
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Code System
Code
Type
Description
Code System
Code
Type
Description
MERCK INDEX
m5757
PRIMARY
Merck Index
CAS
143003-46-7
PRIMARY
NCI_THESAURUS
C74208
PRIMARY
MESH
C070292
PRIMARY
LACTMED
Alglucerase
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
27T56C7KK0
ALGLUCERASE
ACTIVE MOIETY
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Characteristic Attributes
3
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C2532H3835N672O711S16
Biological Half-life
PHARMACOKINETIC
[4 to 11] minutes (average)
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 55600 Da (average)
