HYDROXYPROGESTERONE CAPROATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

First approved in 1956

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H40O4
Molecular Weight	428.6041
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of HYDROXYPROGESTERONE CAPROATE

Structure Search

SMILES

[H][C@@]12CC[C@](OC(=O)CCCCC)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CCC4=CC(=O)CC[C@]34C

InChI

InChIKey=DOMWKUIIPQCAJU-LJHIYBGHSA-N

InChI=1S/C27H40O4/c1-5-6-7-8-24(30)31-27(18(2)28)16-13-23-21-10-9-19-17-20(29)11-14-25(19,3)22(21)12-15-26(23,27)4/h17,21-23H,5-16H2,1-4H3/t21-,22+,23+,25+,26+,27+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C27H40O4
Molecular Weight	428.6041
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Progesterone receptor 61 Target ID: P06401 Gene ID: 5241.0 Gene Symbol: PGR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/18060946	Agonist 2678

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:08:53 UTC 2023` Edited by `admin` on `Fri Dec 15 15:08:53 UTC 2023`
Record UNII	276F2O42F5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HYDROXYPROGESTERONE CAPROATE

Official Name

English

HYDROXYPROGESTERONE CAPROATE [USP MONOGRAPH]

Common Name

English

17.ALPHA.-CAPROYLOXY-P4

Common Name

English

OXIPROGESTERONE CAPROATE

Common Name

English

DEPO-PROLUTON

Brand Name

English

TERALUTIL

Common Name

English

PHARLON

Brand Name

English

17-ALPHA HYDROXYPROGESTERONE CAPROATE

Systematic Name

English

17-OHPC

Common Name

English

HYDROXYPROGESTERONE CAPROATE [MART.]

Common Name

English

17-Hydroxypregn-4-ene-3,20-dione hexanoate

Systematic Name

English

MAKENA

Brand Name

English

HPC

Common Name

English

17.ALPHA.-HYDROXYPREGN-4-ENE-3,20-DIONE HEXANOATE

Systematic Name

English

DELALUTIN

Brand Name

English

17.ALPHA.-HYDROXYPROGESTERONE CAPROATE [MI]

Systematic Name

English

HYDROXYPROGESTERONE HEXANOATE

Common Name

English

HYDROXYPROGESTERONE CAPROATE [ORANGE BOOK]

Common Name

English

17P

Common Name

English

HYDROXYPROGESTERONE CAPROATE [JAN]

Common Name

English

PRIMOLUT DEPOT

Brand Name

English

PREGN-4-ENE-3,20-DIONE, 17-((1-OXOHEXYL)OXY)-

Systematic Name

English

HYDROXYPROGESTERONE CAPROATE [USP-RS]

Common Name

English

PROLUTON DEPOT

Brand Name

English

HYLUTIN

Brand Name

English

PROGE

Common Name

English

3,20-DIOXOPREGN-4-EN-17.ALPHA.-YL CAPROATE

Systematic Name

English

PROCYTE DEPO

Brand Name

English

Hydroxyprogesterone caproate [WHO-DD]

Common Name

English

HYDROXYPROGESTERONE CAPROATE [VANDF]

Common Name

English

HORMOFORT

Brand Name

English

NSC-17592

Code

English

17-ALPHA-HYDROXY-PROGESTERONE CAPROATE

Systematic Name

English

17 ALPHA-HYDROXYPROGESTERONE CAPROATE

Common Name

English

17-HYDROXYPROGESTERONE CAPROATE

Systematic Name

English

hydroxyprogesterone caproate [INN]

Common Name

English

SYNGYNON

Brand Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

445314

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

NCI_THESAURUS

C776

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

FDA ORPHAN DRUG

218706

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL1200848

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

DRUG BANK

DB06789

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

PUBCHEM

169870

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

INN

633

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

WIKIPEDIA

Hydroxyprogesterone caproate

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

MESH

C020365

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

RS_ITEM_NUM

1329006

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

DRUG CENTRAL

4189

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID6043915

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

MERCK INDEX

m6147

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

Merck Index

NSC

17592

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

DAILYMED

276F2O42F5

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

NCI_THESAURUS

C960

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

EVMPD

SUB16009MIG

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

EVMPD

SUB08082MIG

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

FDA UNII

276F2O42F5

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

ECHA (EC/EINECS)

211-138-8

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

RXCUI

12488

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

RxNorm

SMS_ID

100000092822

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

CAS

630-56-8

Created by admin on Fri Dec 15 15:08:53 UTC 2023 , Edited by admin on Fri Dec 15 15:08:53 UTC 2023

PRIMARY

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CYTOCHROME P450 3A7

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Comments:

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Amount:


					276F2O42F5

HYDROXYPROGESTERONE CAPROATE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (UV)

Qualification:

USP

Amount:


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METABOLIC ENZYME -> SUBSTRATE

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Related Record Type Details


					276F2O42F5

HYDROXYPROGESTERONE CAPROATE

ACTIVE MOIETY

Comments:

The ester in HYDROXYPROGESTERONE CAPROATE does not appear to get cleaved in plasma or tissues.

Amount: