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Details

Stereochemistry RACEMIC
Molecular Formula C12H17NO3
Molecular Weight 223.2683
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RIMITEROL

SMILES

O[C@@H]([C@@H]1CCCCN1)C2=CC=C(O)C(O)=C2

InChI

InChIKey=IYMMESGOJVNCKV-JOYOIKCWSA-N
InChI=1S/C12H17NO3/c14-10-5-4-8(7-11(10)15)12(16)9-3-1-2-6-13-9/h4-5,7,9,12-16H,1-3,6H2/t9-,12+/m0/s1

HIDE SMILES / InChI

Molecular Formula C12H17NO3
Molecular Weight 223.2683
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Rimiterol is erythro-(3,4-dihydroxyphenyl)-2-piperidyl-methanol hydrobromide, and is a catecholamine. It is a selective β2-adrenoreceptor agonist, but is not effective as a bronchodilator by the oral route of administration. Rimiterol is available at present as an aerosol, though preliminary studies suggest that it may be of value in the intravenous therapy of severe asthma.

Approval Year

Sample Use Guides

In Vivo Use Guide
As metered-dose aerosol: 250-500 mcg when needed. Max: 8 times/24 hr. Not to repeat dose in <1 hr.
Route of Administration: Respiratory
Substance Class Chemical
Record UNII
26GIW6ZLPH
Record Status Validated (UNII)
Record Version