U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H17NO2
Molecular Weight 219.2796
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ENCYPRATE

SMILES

CCOC(=O)N(CC1=CC=CC=C1)C2CC2

InChI

InChIKey=OGXBVBBMMWSZJO-UHFFFAOYSA-N
InChI=1S/C13H17NO2/c1-2-16-13(15)14(12-8-9-12)10-11-6-4-3-5-7-11/h3-7,12H,2,8-10H2,1H3

HIDE SMILES / InChI

Molecular Formula C13H17NO2
Molecular Weight 219.2796
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Encyprate (MO-1255) is a unique drug in being inactive as an MAO inhibitor in vitro but very active in vivo. It most probably is converted by the body to ethyl-N-benzyl-N-cyclopropylcarbamate which is an active MAOI in vitro. I was studying in the treatment of depression.

Approval Year

PubMed

PubMed

TitleDatePubMed
Clinical studies with MO-1255, a new monoamine oxidase inhibitor antidepressant.
1966 Dec
[A new MAO inhibitor in the therapy of depressions: MO-1255].
1967 May 26
Substance Class Chemical
Created
by admin
on Sat Dec 16 16:16:51 GMT 2023
Edited
by admin
on Sat Dec 16 16:16:51 GMT 2023
Record UNII
26991ZCA4G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ENCYPRATE
INN   USAN  
USAN   INN  
Official Name English
Ethyl N-benzylcyclopropanecarbamate
Common Name English
A-19757
Code English
encyprate [INN]
Common Name English
ENCYPRATE [USAN]
Common Name English
NSC-169504
Code English
MO-1255
Code English
NSC-43799
Code English
CARBAMIC ACID, CYCLOPROPYL(PHENYLMETHYL)-, ETHYL ESTER
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
Code System Code Type Description
FDA UNII
26991ZCA4G
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
CAS
2521-01-9
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
SMS_ID
100000080206
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
EVMPD
SUB06522MIG
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
PUBCHEM
17298
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
NCI_THESAURUS
C87612
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
INN
1961
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104204
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
NSC
43799
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
NSC
169504
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
EPA CompTox
DTXSID90179870
Created by admin on Sat Dec 16 16:16:51 GMT 2023 , Edited by admin on Sat Dec 16 16:16:51 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY