U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C23H29N3O2
Molecular Weight 379.4953
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACC-9358

SMILES

OC1=C(CN2CCCC2)C=C(C=C1CN3CCCC3)C(=O)NC4=CC=CC=C4

InChI

InChIKey=WFYDBDOXSCEPSH-UHFFFAOYSA-N
InChI=1S/C23H29N3O2/c27-22-19(16-25-10-4-5-11-25)14-18(15-20(22)17-26-12-6-7-13-26)23(28)24-21-8-2-1-3-9-21/h1-3,8-9,14-15,27H,4-7,10-13,16-17H2,(H,24,28)

HIDE SMILES / InChI

Molecular Formula C23H29N3O2
Molecular Weight 379.4953
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Ester derivatives of 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol as short-acting antiarrhythmic agents. 1.
1989-08
Electrophysiological effects of ACC-9358, a novel class I antiarrhythmic agent, on isolated canine Purkinje fibers and ventricular muscle.
1989-02
Determination of a novel antiarrhythmic agent ACC-9358 in human plasma by high-performance liquid chromatography.
1988-03
Antiarrhythmic, electrophysiologic and hemodynamic effects of ACC-9358.
1987-12
Development of a thin-layer chromatographic method for the evaluation of antiarrhythmic N-([3,5-di(pyrrolidinylmethyl)-4- hydroxy]benzoyl)aniline (ACC-9358).
1987-11-20
Comparison of the parasympatholytic activity of ACC-9358 and disopyramide.
1986-01
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 17:46:33 GMT 2025
Edited
by admin
on Mon Mar 31 17:46:33 GMT 2025
Record UNII
25576739PX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENZAMIDE, 4-HYDROXY-N-PHENYL-3,5-BIS(1-PYRROLIDINYLMETHYL)-
Preferred Name English
ACC-9358
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID50238174
Created by admin on Mon Mar 31 17:46:33 GMT 2025 , Edited by admin on Mon Mar 31 17:46:33 GMT 2025
PRIMARY
CAS
90446-66-5
Created by admin on Mon Mar 31 17:46:33 GMT 2025 , Edited by admin on Mon Mar 31 17:46:33 GMT 2025
PRIMARY
PUBCHEM
146196
Created by admin on Mon Mar 31 17:46:33 GMT 2025 , Edited by admin on Mon Mar 31 17:46:33 GMT 2025
PRIMARY
FDA UNII
25576739PX
Created by admin on Mon Mar 31 17:46:33 GMT 2025 , Edited by admin on Mon Mar 31 17:46:33 GMT 2025
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY