DPC-083

FC(F)(F)[C@]1(NC(=O)NC2=CC=C(Cl)C=C12)\C=C\C3CC3

InChIKey=UXDWYQAXEGVSPS-GFUIURDCSA-N

InChI=1S/C14H12ClF3N2O/c15-9-3-4-11-10(7-9)13(14(16,17)18,20-12(21)19-11)6-5-8-1-2-8/h3-8H,1-2H2,(H2,19,20,21)/b6-5+/t13-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	1
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors.	2002-06	12019069
4,1-Benzoxazepinone analogues of efavirenz (Sustiva) as HIV-1 reverse transcriptase inhibitors.	2001-06-04	11378361
Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase.	2001-02-12	11212098
3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors.	2001-01-22	11206461
Inhibition of clinically relevant mutant variants of HIV-1 by quinazolinone non-nucleoside reverse transcriptase inhibitors.	2000-05-18	10821714
Expanded-spectrum nonnucleoside reverse transcriptase inhibitors inhibit clinically relevant mutant variants of human immunodeficiency virus type 1.	1999-12	10582878

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:02:46 GMT 2025` Edited by `admin` on `Mon Mar 31 18:02:46 GMT 2025`
Record UNII	2498M8N65F
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BMS-561390

Preferred Name

English

DPC-083

Common Name

English

2(1H)-QUINAZOLINONE, 6-CHLORO-4-((1E)-2-CYCLOPROPYLETHENYL)-3,4-DIHYDRO-4-(TRIFLUOROMETHYL)-, (4S)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

5327770