CLOTHIXAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H28ClN3OS
Molecular Weight	442.017
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(=O)CCN1CCN(CCC=C2C3=CC(Cl)=CC=C3SC4=C2C=CC=C4)CC1

InChI

InChIKey=WXFFTUKVTRHPLQ-UHFFFAOYSA-N

InChI=1S/C24H28ClN3OS/c1-26-24(29)10-12-28-15-13-27(14-16-28)11-4-6-19-20-5-2-3-7-22(20)30-23-9-8-18(25)17-21(19)23/h2-3,5-9,17H,4,10-16H2,1H3,(H,26,29)

HIDE SMILES / InChI

Molecular Formula	C24H28ClN3OS
Molecular Weight	442.017
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.sciencedirect.com/science/article/abs/pii/0024320579900961 | https://patents.google.com/patent/US3196150A/en

Clothixamide is a dopamine antagonist. The compound was invented by Pfizer in the 1960s and is claimed to be useful for the chemotherapy of mental diseases and especially for the control of excited states. Also, clothixamide is claimed to have potent antiemetic properties.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:52:29 GMT 2023` Edited by `admin` on `Sat Dec 16 16:52:29 GMT 2023`
Record UNII	24623E6DZD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOTHIXAMIDE

Common Name

English

1-PIPERAZINEPROPANAMIDE, 4-(3-(2-CHLORO-9H-THIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-

Systematic Name

English

4-(3-(2-CHLOROTHIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-1-PIPERAZINEPROPIONAMIDE

Systematic Name

English

clotixamide [INN]

Common Name

English

CLOTIXAMIDE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66883