ATIBUCLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:02:45 GMT 2025` Edited by `admin` on `Wed Apr 02 00:02:45 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	23IQ3PO968
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ATIBUCLIMAB

Official Name

English

IC-14

Preferred Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA.-CHAIN, DIMER

Common Name

English

IC14

Code

English

IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14)

Common Name

English

Atibuclimab [WHO-DD]

Common Name

English

atibuclimab [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

650418

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

Code System Code Type Description

INN

11865

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

PRIMARY

SMS_ID

300000027016

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

PRIMARY

NCI_THESAURUS

C172657

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

PRIMARY

CAS

2417175-94-9

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

PRIMARY

FDA UNII

23IQ3PO968

Created by admin on Wed Apr 02 00:02:45 GMT 2025 , Edited by admin on Wed Apr 02 00:02:45 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_129	4_218
2_142	2_198
2_256	2_316
1_129	3_218
2_362	2_420
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_142	1_198
1_221	2_221
1_224	2_224
1_256	1_316
1_362	1_420

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_292
N	2_292

Related Record Type Details


					0X8U3V6C5K

MONOCYTE DIFFERENTIATION ANTIGEN CD14

TARGET -> INHIBITOR

Related Record Type Details


					23IQ3PO968

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_442] [2_442]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL