Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 19:12:52 GMT 2023
by
admin
on
Sat Dec 16 19:12:52 GMT 2023
|
| Protein Sub Type | |
| Sequence Type | COMPLETE |
| Record UNII |
22DXZ2U99R
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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22DXZ2U99R
Created by
admin on Sat Dec 16 19:12:52 GMT 2023 , Edited by admin on Sat Dec 16 19:12:52 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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|
ACTIVATOR -> TARGET |
MTK458 binds PINK1 directly and stabilizes it in an active conformation. Indeed, PINK1 activation was found to be caused directly by MTK458 and not its metabolite(s).
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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