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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H30O2
Molecular Weight 302.451
Optical Activity ( + )
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL-1-TESTOSTERONE

SMILES

C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

InChI

InChIKey=JRNSSSJKIGAFCT-YDSAWKJFSA-N
InChI=1S/C20H30O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,13,15-17,22H,4-5,7-8,10-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H30O2
Molecular Weight 302.451
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 7 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Methyl-1-testosterone(M1T)(17alpha-hydroxy-17-methyl- 5-androst-1-en-3-one) is a new designer steroid that is most likely produced to circumvent the legal restrictions. It is advertised to be highly anabolic and moderately androgenic and not convertible to estrogens. However, in scientific literature, it was reported to show anabolic properties of 25% and androgenic properties of 50% compared with testosterone propionate after im injection in castrated rats. In February 2006, Health Canada (Federal Department) warned consumers not to use M1T-containing products because of potentially serious health risks such as liver disorders and hardening of the arteries. Since 2006, M1T is explicitly listed on the World Anti-Doping Agency list of prohibited substances, and therefore, its use by athletes is prohibited.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
3.0 nM [EC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
For amplifying performance and physique gains, recommended dosages range from 5mg to 20mg. Dosages above 20mg is not recommended.
Route of Administration: Oral
In Vitro Use Guide
In the yeast androgen screen (YAS), M1T induced AR-dependent gene activity in a dose-dependent manner. The EC50 was consistent with the EC50 of the reference DHT (3 x 10-9 M).
Substance Class Chemical
Record UNII
21O907N0NH
Record Status Validated (UNII)
Record Version