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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H30O2
Molecular Weight 302.451
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL-1-TESTOSTERONE

SMILES

[H][C@@]12CC[C@](C)(O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@@]4([H])CC(=O)C=C[C@]34C

InChI

InChIKey=JRNSSSJKIGAFCT-YDSAWKJFSA-N
InChI=1S/C20H30O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,13,15-17,22H,4-5,7-8,10-12H2,1-3H3/t13-,15+,16-,17-,18-,19-,20-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H30O2
Molecular Weight 302.451
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 7 / 7
E/Z Centers 0
Optical Activity UNSPECIFIED

Methyl-1-testosterone(M1T)(17alpha-hydroxy-17-methyl- 5-androst-1-en-3-one) is a new designer steroid that is most likely produced to circumvent the legal restrictions. It is advertised to be highly anabolic and moderately androgenic and not convertible to estrogens. However, in scientific literature, it was reported to show anabolic properties of 25% and androgenic properties of 50% compared with testosterone propionate after im injection in castrated rats. In February 2006, Health Canada (Federal Department) warned consumers not to use M1T-containing products because of potentially serious health risks such as liver disorders and hardening of the arteries. Since 2006, M1T is explicitly listed on the World Anti-Doping Agency list of prohibited substances, and therefore, its use by athletes is prohibited.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
3.0 nM [EC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
[Component analysis of a new anabolic androgenic steroid and its monitoring research in human urine].
2010 Jan
Endocrine characterization of the designer steroid methyl-1-testosterone: investigations on tissue-specific anabolic-androgenic potency, side effects, and metabolism.
2011 Dec
Acute Kidney Injury Due to Interaction of Methyl-1-testosterone with Ciclosporin Metabolism in a Patient with Severe Atopic Dermatitis.
2013 Dec
Patents

Sample Use Guides

For amplifying performance and physique gains, recommended dosages range from 5mg to 20mg. Dosages above 20mg is not recommended.
Route of Administration: Oral
In the yeast androgen screen (YAS), M1T induced AR-dependent gene activity in a dose-dependent manner. The EC50 was consistent with the EC50 of the reference DHT (3 x 10-9 M).
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:03:19 GMT 2023
Edited
by admin
on Sat Dec 16 08:03:19 GMT 2023
Record UNII
21O907N0NH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHYL-1-TESTOSTERONE
Common Name English
OXANDROLONE IMPURITY, .DELTA.1-MESTALONE- [USP IMPURITY]
Common Name English
17.ALPHA.-METHYL-17.BETA.-HYDROXY-.DELTA.1-5.ALPHA.-ANDROSTEN-3-ONE
Systematic Name English
17-ALPHA-METHYL-1-TESTOSTERONE
Common Name English
17.BETA.-HYDROXY-17.ALPHA.-METHYL-5.ALPHA.-ANDROST-1-EN-3-ONE
Systematic Name English
17.ALPHA.-METHYL-17.BETA.-HYDROXY-5.ALPHA.-ANDROST-1-EN-3-ONE
Systematic Name English
ANDROST-1-EN-3-ONE, 17-HYDROXY-17-METHYL-, (5.ALPHA.,17.BETA.)-
Systematic Name English
17.BETA.-HYDROXY-17.ALPHA.-METHYL-5.ALPHA.-ANDROST-1-ENE-3-ONE
Systematic Name English
(+)-METHYL-1-TESTOSTERONE
Common Name English
SC-11195
Code English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-Methyl-1-testosterone
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
DEA NO. 4000
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID20879831
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
DRUG BANK
DB01572
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
CAS
65-04-3
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
PUBCHEM
7092657
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
CAS
18167-94-7
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY
WIKIPEDIA
METHYL-1-TESTOSTERONE
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
FDA UNII
21O907N0NH
Created by admin on Sat Dec 16 08:03:19 GMT 2023 , Edited by admin on Sat Dec 16 08:03:19 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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ACTIVE MOIETY