FURALAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7N5O3
Molecular Weight	233.1836
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC=C(\C=C\C2=CC=C(O2)[N+]([O-])=O)N=N1

InChI

InChIKey=RWOLIGKRDWLZSV-OWOJBTEDSA-N

InChI=1S/C9H7N5O3/c10-9-11-5-6(12-13-9)1-2-7-3-4-8(17-7)14(15)16/h1-5H,(H2,10,11,13)/b2-1+

HIDE SMILES / InChI

Molecular Formula	C9H7N5O3
Molecular Weight	233.1836
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5312990 | https://www.kegg.jp/entry/D02511

Furalazine is an antibacterial agent that was studied for the treatment of typical cholera symptoms. However, information about the further development of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Antibiotic-resistant strains of E1 Tor vibrio in the Philippines and the use of furalazine for chemotherapy.	1970	5312990

Sample Use Guides

In Vivo Use Guide

The treatment with FURALAZINE (FL) was tested on 33 adults and 15 children who revealed typical cholera symptoms on admission. The intravenous fluid requirements of patients receiving FL were very similar to those of patients receiving CP.

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:15:43 UTC 2023` Edited by `admin` on `Fri Dec 15 16:15:43 UTC 2023`
Record UNII	2133JVQ6VE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FURALAZINE

Official Name

English

NFT

Common Name

English

3-AMINO-6-(5-NITROFURYLETHENYL)-1,2,4-TRIAZINE

Systematic Name

English

3-AMINO-6-(2-(5-NITRO-2-FURYL)VINYL)-1,2,4-TRIAZINE

Systematic Name

English

PANFURAN

Brand Name

English

AS-TRIAZINE, 3-AMINO-6-(2-(5-NITRO-2-FURYL)VINYL)-

Common Name

English

NIFURALAZINE

Common Name

English

1,2,4-TRIAZIN-3-AMINE, 6-(2-(5-NITRO-2-FURANYL)ETHENYL)-

Systematic Name

English

furalazine [INN]

Common Name

English

3-AMINO-6-(2-(5-NITRO-2-FURYL)VINYL)-AS-TRIAZINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C254