U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 16:16:37 GMT 2023
Edited
by admin
on Sat Dec 16 16:16:37 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Parvoviridae
Organism Genus Dependoparvovirus
Organism Species adeno-associated dependoparvovirus a
Infraspecific Type SUBSTRAIN
Infraspecific Name AAV1-LPLS447X
Part WHOLE
Record UNII
20OK4AFR4Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALIPOGENE TIPARVOVEC
EMA EPAR   INN   WHO-DD  
INN  
Official Name English
GLYBERA
Brand Name English
DNA (SYNTHETIC ADENO-ASSOCIATED VIRUS 1 VECTOR AMT-011), COMPLEX WITH PROTEIN VP1 (ADENO-ASSOCIATED VIRUS 1) AND PROTEIN VP2 (ADENO-ASSOCIATED VIRUS 1) AND PROTEIN VP3 (ADENO-ASSOCIATED VIRUS 1)
Common Name English
RECOMBINANT ADENO-ASSOCIATED VIRUS SEROTYPE 1 (AAV1) VECTOR EXPRESSING THE S447X VARIANT OF THE HUMAN LIPOPROTEIN LIPASE (LPL) GENE
Common Name English
ALIPOGENE TIPARVOVEC [EMA EPAR]
Common Name English
Alipogene tiparvovec [WHO-DD]
Common Name English
alipogene tiparvovec [INN]
Common Name English
Classification Tree Code System Code
WHO-ATC C10AX10
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
EU-Orphan Drug EU/3/04/194
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
WHO-VATC QC10AX10
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
Code System Code Type Description
DRUG CENTRAL
5172
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
INN
8987
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
WIKIPEDIA
ALIPOGENE TIPARVOVEC
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
NCI_THESAURUS
C166528
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
CAS
929881-05-0
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
EVMPD
SUB30966
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108304
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
FDA UNII
20OK4AFR4Y
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
DRUG BANK
DB13521
Created by admin on Sat Dec 16 16:16:37 GMT 2023 , Edited by admin on Sat Dec 16 16:16:37 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR ALIPOGENE TIPARVOVEC DNA 28C08R70ZR