ALIPOGENE TIPARVOVEC

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 07:34:14 GMT 2025` Edited by `admin` on `Wed Apr 02 07:34:14 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependoparvovirus
Organism Species	adeno-associated dependoparvovirus a
Infraspecific Type	SUBSTRAIN
Infraspecific Name	AAV1-LPLS447X
Part	whole
Record UNII	20OK4AFR4Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALIPOGENE TIPARVOVEC

Official Name

English

alipogene tiparvovec [INN]

Preferred Name

English

GLYBERA

Brand Name

English

DNA (SYNTHETIC ADENO-ASSOCIATED VIRUS 1 VECTOR AMT-011), COMPLEX WITH PROTEIN VP1 (ADENO-ASSOCIATED VIRUS 1) AND PROTEIN VP2 (ADENO-ASSOCIATED VIRUS 1) AND PROTEIN VP3 (ADENO-ASSOCIATED VIRUS 1)

Common Name

English

RECOMBINANT ADENO-ASSOCIATED VIRUS SEROTYPE 1 (AAV1) VECTOR EXPRESSING THE S447X VARIANT OF THE HUMAN LIPOPROTEIN LIPASE (LPL) GENE

Common Name

English

ALIPOGENE TIPARVOVEC [EMA EPAR]

Common Name

English

Alipogene tiparvovec [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

C10AX10

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

EU-Orphan Drug

EU/3/04/194

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

WHO-VATC

QC10AX10

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

Code System Code Type Description

SMS_ID

100000115623

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

PRIMARY

DRUG CENTRAL

5172

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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INN

8987

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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WIKIPEDIA

ALIPOGENE TIPARVOVEC

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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NCI_THESAURUS

C166528

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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CAS

929881-05-0

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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EVMPD

SUB30966

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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ChEMBL

CHEMBL2108304

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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FDA UNII

20OK4AFR4Y

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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DRUG BANK

DB13521

Created by admin on Wed Apr 02 07:34:14 GMT 2025 , Edited by admin on Wed Apr 02 07:34:14 GMT 2025

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Related Record Type Details


					20OK4AFR4Y

ALIPOGENE TIPARVOVEC

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
GENE_EXPRESSION VECTOR					ALIPOGENE TIPARVOVEC DNA	28C08R70ZR