VIQUALINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H26N2O
Molecular Weight	310.4332
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C=C1)N=CC=C2CCC[C@@H]3CCNC[C@@H]3C=C

InChI

InChIKey=XFXANHWIBFMEOY-JKSUJKDBSA-N

InChI=1S/C20H26N2O/c1-3-15-14-21-11-9-16(15)5-4-6-17-10-12-22-20-8-7-18(23-2)13-19(17)20/h3,7-8,10,12-13,15-16,21H,1,4-6,9,11,14H2,2H3/t15-,16+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H26N2O
Molecular Weight	310.4332
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3075725 | https://www.ncbi.nlm.nih.gov/pubmed/7632745

Viqualine (also known as PK 5078) was developed as an antidepressant; however, it has never been marketed. Viqualine acts as an inhibitor of the serotonin reuptake and release and possesses diazepam-like actions. In addition, was studied the ability of this compound to reduce alcohol consumption and that was not an antidepressant effect.

Approval Year

PubMed

Title	Date	PubMed
The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives.	1984 Feb	6717757
Viqualine in resistant depression: a double-blind, placebo-controlled trial.	1988	3075725

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:22:33 UTC 2023` Edited by `admin` on `Fri Dec 15 15:22:33 UTC 2023`
Record UNII	1Y3A5E2L1J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VIQUALINE

Official Name

English

VIQUALINE [MART.]

Common Name

English

viqualine [INN]

Common Name

English

6-METHOXY-4-(3-((3R,4R)-3-VINYL-4-PIPERIDYL)PROPYL)QUINOLINE.

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265