VIQUALINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H26N2O
Molecular Weight	310.4332
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C2N=CC=C(CCC[C@@H]3CCNC[C@@H]3C=C)C2=C1

InChI

InChIKey=XFXANHWIBFMEOY-JKSUJKDBSA-N

InChI=1S/C20H26N2O/c1-3-15-14-21-11-9-16(15)5-4-6-17-10-12-22-20-8-7-18(23-2)13-19(17)20/h3,7-8,10,12-13,15-16,21H,1,4-6,9,11,14H2,2H3/t15-,16+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H26N2O
Molecular Weight	310.4332
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3075725 | https://www.ncbi.nlm.nih.gov/pubmed/7632745

Viqualine (also known as PK 5078) was developed as an antidepressant; however, it has never been marketed. Viqualine acts as an inhibitor of the serotonin reuptake and release and possesses diazepam-like actions. In addition, was studied the ability of this compound to reduce alcohol consumption and that was not an antidepressant effect.

Approval Year

PubMed

Title	Date	PubMed
Pharmacotherapy in alcoholism.	1995	7632745
Viqualine in resistant depression: a double-blind, placebo-controlled trial.	1988	3075725
The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives.	1984-02	6717757

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:55:37 GMT 2025` Edited by `admin` on `Mon Mar 31 17:55:37 GMT 2025`
Record UNII	1Y3A5E2L1J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VIQUALINE

Official Name

English

6-METHOXY-4-(3-((3R,4R)-3-VINYL-4-PIPERIDYL)PROPYL)QUINOLINE.

Preferred Name

English

VIQUALINE [MART.]

Common Name

English

viqualine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265