ISOSPAGLUMIC ACID

Possibly Marketed Outside US

CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChIKey=OPVPGKGADVGKTG-BQBZGAKWSA-N

InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

ISOSPAGLUMIC ACID is used as an antiallergic agent.

Primary Target	Pharmacology	Condition	Potency
Glutamate carboxypeptidase II 4	Inhibitor 8,297		8.5 µM [Ki]

Show entries

Title	Date	PubMed
N-acetylaspartate is an axon-specific marker of mature white matter in vivo: a biochemical and immunohistochemical study on the rat optic nerve.	2002 Jan	11782984
N-Acetyl-L-aspartyl-L-glutamate changes functional and structural properties of rat blood-brain barrier.	2002 Jan 11	11755246
Prostate targeting ligands based on N-acetylated alpha-linked acidic dipeptidase.	2003 Jul 18	12849974
Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.	2003 Jul 30	12928106
Protection against glucose-induced neuronal death by NAAG and GCP II inhibition is regulated by mGluR3.	2004 Apr	15030392