PANURAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H25N3O2
Molecular Weight	387.4742
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C(NC1CCN(CC2=CC=C3C=CC=CC3=C2)CC1)NC(=O)C4=CC=CC=C4

InChI

InChIKey=AQFFJGJVFJCQQL-UHFFFAOYSA-N

InChI=1S/C24H25N3O2/c28-23(20-7-2-1-3-8-20)26-24(29)25-22-12-14-27(15-13-22)17-18-10-11-19-6-4-5-9-21(19)16-18/h1-11,16,22H,12-15,17H2,(H2,25,26,28,29)

HIDE SMILES / InChI

Molecular Formula	C24H25N3O2
Molecular Weight	387.4742
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6514142

Panuramine, a selective inhibitor of uptake of 5-hydroxytryptamine that was studied as an antidepressant, however, has never been marketed.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Sodium-dependent serotonin transporter 40 Target ID: P31652 Gene ID: 25553.0 Gene Symbol: Slc6a4 Target Organism: Rattus norvegicus (Rat) Sources: https://www.ncbi.nlm.nih.gov/pubmed/6514142	Inhibitor 8297		22.0 nM [IC50]

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:09:22 GMT 2023` Edited by `admin` on `Fri Dec 15 16:09:22 GMT 2023`
Record UNII	1UWS3T8EAB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PANURAMINE

Official Name

English

panuramine [INN]

Common Name

English

1-BENZOYL-3-(1-(2-NAPHTHYLMETHYL)-4-PIPERIDYL)UREA

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265