FENALCOMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C20H27NO2
Molecular Weight	313.4339
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENALCOMINE

Structure Search

SMILES

CCC(O)C1=CC=C(OCCNC(C)CC2=CC=CC=C2)C=C1

InChI

InChIKey=DOBLSWXRNYSVDC-UHFFFAOYSA-N

InChI=1S/C20H27NO2/c1-3-20(22)18-9-11-19(12-10-18)23-14-13-21-16(2)15-17-7-5-4-6-8-17/h4-12,16,20-22H,3,13-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H27NO2
Molecular Weight	313.4339
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/1134178 | https://www.ncbi.nlm.nih.gov/pubmed/779586 | http://www.druglead.com/cds/Fenalcomine.html

Fenalcomine is a coronary vasodilator, cardiotonic and local anesthetic agent. It was studied in the treatment of angina pectoris.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Clinical study of a new anti-angina pectoris agent: Fenalcomine hydrochloride].	1975 Jan	1134178
[Study of the action of fenalcomine chlorhydrate using ergometric tests].	1975 May-Jun	1096749
[Clinical study of fenalcomine chlorhydrate in 30 cases of angina pectoris].	1976 May-Jun	779586
Fenalcomine hydrochloride inhibits the action of PG on the smooth muscle but stimulates that of TXA2.	1980	7386277

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:29:42 GMT 2023` Edited by `admin` on `Sat Dec 16 17:29:42 GMT 2023`
Record UNII	1TBQ3A47P8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FENALCOMINE

Official Name

English

.ALPHA.-ETHYL-P-(2-((.ALPHA.-METHYLPHENETHYL)AMINO)ETHOXY)BENZYL ALCOHOL

Common Name

English

fenalcomine [INN]

Common Name

English

Fenalcomine [WHO-DD]

Common Name

English

FENALCOMINE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

Code System Code Type Description

CAS

34616-39-2

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

PRIMARY

SMS_ID

100000081241

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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ChEMBL

CHEMBL2106300

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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EPA CompTox

DTXSID10865723

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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INN

3380

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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DRUG CENTRAL

1144

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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MERCK INDEX

m184

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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Merck Index

NCI_THESAURUS

C65636

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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MESH

C001424

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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FDA UNII

1TBQ3A47P8

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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PUBCHEM

71934

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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EVMPD

SUB07536MIG

Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023

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					1TBQ3A47P8

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