U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry MIXED
Molecular Formula C20H27NO2
Molecular Weight 313.4339
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FENALCOMINE

SMILES

CCC(O)C1=CC=C(OCCNC(C)CC2=CC=CC=C2)C=C1

InChI

InChIKey=DOBLSWXRNYSVDC-UHFFFAOYSA-N
InChI=1S/C20H27NO2/c1-3-20(22)18-9-11-19(12-10-18)23-14-13-21-16(2)15-17-7-5-4-6-8-17/h4-12,16,20-22H,3,13-15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C20H27NO2
Molecular Weight 313.4339
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Fenalcomine is a coronary vasodilator, cardiotonic and local anesthetic agent. It was studied in the treatment of angina pectoris.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Study of the action of fenalcomine chlorhydrate using ergometric tests].
1975 May-Jun
[Clinical study of fenalcomine chlorhydrate in 30 cases of angina pectoris].
1976 May-Jun
Fenalcomine hydrochloride inhibits the action of PG on the smooth muscle but stimulates that of TXA2.
1980
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:29:42 GMT 2023
Edited
by admin
on Sat Dec 16 17:29:42 GMT 2023
Record UNII
1TBQ3A47P8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FENALCOMINE
INN   MI   WHO-DD  
INN  
Official Name English
.ALPHA.-ETHYL-P-(2-((.ALPHA.-METHYLPHENETHYL)AMINO)ETHOXY)BENZYL ALCOHOL
Common Name English
fenalcomine [INN]
Common Name English
Fenalcomine [WHO-DD]
Common Name English
FENALCOMINE [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29707
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
Code System Code Type Description
CAS
34616-39-2
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
SMS_ID
100000081241
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106300
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID10865723
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
INN
3380
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
DRUG CENTRAL
1144
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
MERCK INDEX
m184
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY Merck Index
NCI_THESAURUS
C65636
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
MESH
C001424
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
FDA UNII
1TBQ3A47P8
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
PUBCHEM
71934
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
EVMPD
SUB07536MIG
Created by admin on Sat Dec 16 17:29:42 GMT 2023 , Edited by admin on Sat Dec 16 17:29:42 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY