Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C13H20Cl2N2 |
| Molecular Weight | 275.217 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCN(C)CCC1=CC=C(Cl)C(Cl)=C1
InChI
InChIKey=MGVRNMUKTZOQOW-UHFFFAOYSA-N
InChI=1S/C13H20Cl2N2/c1-16(2)8-9-17(3)7-6-11-4-5-12(14)13(15)10-11/h4-5,10H,6-9H2,1-3H3
| Molecular Formula | C13H20Cl2N2 |
| Molecular Weight | 275.217 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. | 2010-06-10 |
|
| The Antinociceptive Effect of Sigma-1 Receptor Antagonist, BD1047, in a Capsaicin Induced Headache Model in Rats. | 2009-12 |
|
| Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice. | 2008-07 |
|
| Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation. | 2008-01 |
|
| Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. | 2007-12 |
|
| Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory. | 2006-07 |
|
| Cocaine and sigma-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model. | 2005-12 |
|
| The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan. | 2005-04 |
|
| Role of NMDA receptor subtypes in the induction of catalepsy and increase in Fos protein expression after administration of haloperidol. | 2004-06-11 |
|
| Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward. | 2003-05-01 |
|
| Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. | 2000-09-11 |
|
| Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity. | 1999-04-16 |
|
| Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism. | 1995-07-14 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:30:59 GMT 2025
by
admin
on
Mon Mar 31 23:30:59 GMT 2025
|
| Record UNII |
1S3X75QGDO
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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Preferred Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
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DTXSID70160640
Created by
admin on Mon Mar 31 23:30:59 GMT 2025 , Edited by admin on Mon Mar 31 23:30:59 GMT 2025
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1S3X75QGDO
Created by
admin on Mon Mar 31 23:30:59 GMT 2025 , Edited by admin on Mon Mar 31 23:30:59 GMT 2025
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188914
Created by
admin on Mon Mar 31 23:30:59 GMT 2025 , Edited by admin on Mon Mar 31 23:30:59 GMT 2025
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138356-20-4
Created by
admin on Mon Mar 31 23:30:59 GMT 2025 , Edited by admin on Mon Mar 31 23:30:59 GMT 2025
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BD-1047
Created by
admin on Mon Mar 31 23:30:59 GMT 2025 , Edited by admin on Mon Mar 31 23:30:59 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
