ALTEPLASE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Peroxisome proliferator-activated receptor gamma 118 Target ID: P37231\|\|\|Q15179 Gene ID: 5468.0 Gene Symbol: PPARG Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16033271	Activator 1447
Lysophosphatidic acid receptor 1 4 Target ID: Q92633 Gene ID: 1902.0 Gene Symbol: LPAR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16033271	Antagonist 2849		10.0 µM [IC50]
Lysophosphatidic acid receptor 2 4 Target ID: Q9HBW0 Gene ID: 9170.0 Gene Symbol: LPAR2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16033271	Antagonist 2849		5.5 µM [IC50]
Lysophosphatidic acid receptor 3 4 Target ID: Q9UBY5 Gene ID: 23566.0 Gene Symbol: LPAR3 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16033271	Antagonist 2849		3.1 µM [IC50]

Substance Class	Mixture Created by `admin` on `Wed Apr 02 05:00:32 GMT 2025` Edited by `admin` on `Wed Apr 02 05:00:32 GMT 2025`
Record UNII	1RXS4UE564
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ALTEPLASE

Official Name

English

ALTEPLASE (GENETICAL RECOMBINATION)

Preferred Name

English

ALTEPLASE [MART.]

Common Name

English

ALTEPLASE [USAN]

Common Name

English

ALTEPLASE FOR INJECTION

Common Name

English

alteplase [INN]

Common Name

English

ALTEPLASE (GENETICAL RECOMBINATION) [JAN]

Common Name

English

ALTEPLASE [VANDF]

Common Name

English

TISSUE PLASMINOGEN ACTIVATOR, RECOMBINANT

Common Name

English

ALTEPLASE FOR INJECTION [EP MONOGRAPH]

Common Name

English

ACTIVASE

Brand Name

English

ACTILYSE

Brand Name

English

ALTEPLASE [JAN]

Common Name

English

ALTEPLASE, RECOMBINANT

Common Name

English

ALTEPLASE [PURPLE BOOK CDER]

Common Name

English

EC 3.4.21.68

Common Name

English

RT-PA

Code

English

PLASMINOGEN ACTIVATOR (HUMAN TISSUE-TYPE PROTEIN MOIETY)

Common Name

English

TISSUE PLASMINOGEN ACTIVATOR ALTEPLASE

Common Name

English

TPA

Common Name

English

ALTEPLASE [USP MONOGRAPH]

Common Name

English

Alteplase [WHO-DD]

Common Name

English

ALTEPLASE,RECOMBINANT [VANDF]

Common Name

English

TISSUE PLASMINOGEN ACTIVATOR ALTEPLASE [MI]

Common Name

English

ALTEPLASE,RECOMBINANT

Common Name

English

Classification Tree Code System Code

WHO-VATC

QB01AD02

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

FDA ORPHAN DRUG

163502

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

FDA ORPHAN DRUG

331410

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

WHO-ATC

B01AD02

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

FDA ORPHAN DRUG

431414

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

WHO-ATC

S01XA13

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

WHO-VATC

QS01XA13

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

NCI_THESAURUS

C29750

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

Code System Code Type Description

LACTMED

Alteplase

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

DRUG CENTRAL

5141

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

ChEMBL

CHEMBL1201593

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

DAILYMED

1RXS4UE564

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

EVMPD

SUB32223

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

WIKIPEDIA

Alteplase

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

EVMPD

SUB126952

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

RXCUI

8410

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

RxNorm

DRUG BANK

DB00009

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

EVMPD

SUB05378MIG

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

SMS_ID

100000089921

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

FDA UNII

1RXS4UE564

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

NCI_THESAURUS

C39607

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

USAN

X-35

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

IUPHAR

4985

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

INN

5975

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

MESH

D010959

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

MERCK INDEX

m10894

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

Merck Index

CAS

105857-23-6

Created by admin on Wed Apr 02 05:00:32 GMT 2025 , Edited by admin on Wed Apr 02 05:00:32 GMT 2025

PRIMARY

All of the following components must be present:


					SHA5M53GCA

ALTEPLASE SINGLE CHAIN


					WTT2Q69J6E

ALTEPLASE TWO CHAIN PROTEIN

Related Record Type Details


					1EF190B6M7

SUBSTRATE->ENZYME


					1EF190B6M7

TARGET->ENZYME


					AQ4K8I4R6F

FIBRIN

SUBSTRATE->ENZYME

Related Record Type Details


					1RXS4UE564

ALTEPLASE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

Definition References