PIRIDICILLIN SODIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C32H34N5O11S2.Na
Molecular Weight	751.759
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](NC(=O)C3=CC=C(NC3=O)C4=CC=C(C=C4)S(=O)(=O)N(CCO)CCO)C5=CC=C(O)C=C5)C([O-])=O

InChI

InChIKey=CHEUORCVUSORLI-BQZVOSRDSA-M

InChI=1S/C32H35N5O11S2.Na/c1-32(2)25(31(45)46)37-29(44)24(30(37)49-32)35-28(43)23(18-3-7-19(40)8-4-18)34-27(42)21-11-12-22(33-26(21)41)17-5-9-20(10-6-17)50(47,48)36(13-15-38)14-16-39;/h3-12,23-25,30,38-40H,13-16H2,1-2H3,(H,33,41)(H,34,42)(H,35,43)(H,45,46);/q;+1/p-1/t23-,24-,25+,30-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C32H34N5O11S2
Molecular Weight	728.769
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/468737 | https://www.ncbi.nlm.nih.gov/pubmed/7235679 | https://www.ncbi.nlm.nih.gov/pubmed/6270049

Piridicillin is the semi-synthetic penicillin. It has exhibited broad-spectrum activity in vitro against gram-positive cocci, except penicillin G-resistant Staphylococcus aureus, and against gram-negative bacilli. Piridicillin is reported to be more active in-vitro than piperacillin, azlocillin or ticarcillin against Ps. aeruginosa. It is unstable at alkaline pH and displays marked inoculum independence.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:25:35 GMT 2023` Edited by `admin` on `Fri Dec 15 16:25:35 GMT 2023`
Record UNII	1Q728MH9P9
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PIRIDICILLIN SODIUM

Official Name

English

PIRIDICILLIN SODIUM [USAN]

Common Name

English

CL-867

Code

English

SODIUM (2S,5R,6R)-6-((R)-2-(6-(P-(BIS(2-HYDROXYETHYL)SULFAMOYL)PHENYL)-1,2-DIHYDRO-2-OXONICOTINAMIDO)-2-(P-HYDROXYPHENYL)ACETAMIDO)-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1500