CHF-4227

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H33NO4
Molecular Weight	471.5873
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(C=C1)C2=C(CC3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5OC2

InChI

InChIKey=ZUDXUNPSRMREOJ-UHFFFAOYSA-N

InChI=1S/C30H33NO4/c1-33-25-12-7-23(8-13-25)29-21-35-30-20-24(32)9-14-27(30)28(29)19-22-5-10-26(11-6-22)34-18-17-31-15-3-2-4-16-31/h5-14,20,32H,2-4,15-19,21H2,1H3

HIDE SMILES / InChI

Molecular Formula	C30H33NO4
Molecular Weight	471.5873
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen.	2002 Oct	12235251
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.	2005 Dec	16294271
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Single and multiple ascending dose studies of a novel tissue-selective oestrogen receptor modulator, CHF 4227, in healthy postmenopausal women.	2007 Sep	17367495

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:24:53 UTC 2023` Edited by `admin` on `Sat Dec 16 08:24:53 UTC 2023`
Record UNII	1O98089Q9M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHF-4227

Common Name

English

2H-1-BENZOPYRAN-7-OL, 3-(4-METHOXYPHENYL)-4-((4-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)METHYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

1O98089Q9M