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Details

Stereochemistry ACHIRAL
Molecular Formula C30H33NO4
Molecular Weight 471.5873
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHF-4227

SMILES

COC1=CC=C(C=C1)C2=C(CC3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5OC2

InChI

InChIKey=ZUDXUNPSRMREOJ-UHFFFAOYSA-N
InChI=1S/C30H33NO4/c1-33-25-12-7-23(8-13-25)29-21-35-30-20-24(32)9-14-27(30)28(29)19-22-5-10-26(11-6-22)34-18-17-31-15-3-2-4-16-31/h5-14,20,32H,2-4,15-19,21H2,1H3

HIDE SMILES / InChI

Molecular Formula C30H33NO4
Molecular Weight 471.5873
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.
2005 Dec
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006 Nov
Single and multiple ascending dose studies of a novel tissue-selective oestrogen receptor modulator, CHF 4227, in healthy postmenopausal women.
2007 Sep
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:24:53 UTC 2023
Edited
by admin
on Sat Dec 16 08:24:53 UTC 2023
Record UNII
1O98089Q9M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHF-4227
Common Name English
2H-1-BENZOPYRAN-7-OL, 3-(4-METHOXYPHENYL)-4-((4-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)METHYL)-
Systematic Name English
Code System Code Type Description
FDA UNII
1O98089Q9M
Created by admin on Sat Dec 16 08:24:53 UTC 2023 , Edited by admin on Sat Dec 16 08:24:53 UTC 2023
PRIMARY
PUBCHEM
9912639
Created by admin on Sat Dec 16 08:24:53 UTC 2023 , Edited by admin on Sat Dec 16 08:24:53 UTC 2023
PRIMARY
CAS
444643-64-5
Created by admin on Sat Dec 16 08:24:53 UTC 2023 , Edited by admin on Sat Dec 16 08:24:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID50196184
Created by admin on Sat Dec 16 08:24:53 UTC 2023 , Edited by admin on Sat Dec 16 08:24:53 UTC 2023
PRIMARY
ChEMBL
CHEMBL3545355
Created by admin on Sat Dec 16 08:24:53 UTC 2023 , Edited by admin on Sat Dec 16 08:24:53 UTC 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY