CHF-4227

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H33NO4
Molecular Weight	471.5873
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(C=C1)C2=C(CC3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5OC2

InChI

InChIKey=ZUDXUNPSRMREOJ-UHFFFAOYSA-N

InChI=1S/C30H33NO4/c1-33-25-12-7-23(8-13-25)29-21-35-30-20-24(32)9-14-27(30)28(29)19-22-5-10-26(11-6-22)34-18-17-31-15-3-2-4-16-31/h5-14,20,32H,2-4,15-19,21H2,1H3

HIDE SMILES / InChI

Molecular Formula	C30H33NO4
Molecular Weight	471.5873
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Single and multiple ascending dose studies of a novel tissue-selective oestrogen receptor modulator, CHF 4227, in healthy postmenopausal women.	2007-09	17367495
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.	2005-12	16294271
Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen.	2002-10	12235251

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:03:39 GMT 2025` Edited by `admin` on `Mon Mar 31 22:03:39 GMT 2025`
Record UNII	1O98089Q9M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2H-1-BENZOPYRAN-7-OL, 3-(4-METHOXYPHENYL)-4-((4-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)METHYL)-

Preferred Name

English

CHF-4227

Common Name

English

Code System Code Type Description

FDA UNII

1O98089Q9M