Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C20H23NO4 |
Molecular Weight | 341.4009 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC3=C(C(OC)=C(OC)C=C3)C4=C1C(CCN2C)=CC(OC)=C4O
InChI
InChIKey=IDQUPXZJURZAGF-ZDUSSCGKSA-N
InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1
Molecular Formula | C20H23NO4 |
Molecular Weight | 341.4009 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Corydine is a naturally occurring compound which can be extracted from plants such as Chelidonium majus, Corydalis marschalliana, C. bulbosa, C slivenensis, Glaucium grandiflorum. Corydine has shown some efficacy as an anti-cancer compound in several cell models and was examined along with related compounds from Stephania dinklagei for antiprotozoal activities. (+)- and (-)- Corydine were tested as neuromuscular blocking agents were it was found that there was a modest preference for (+)-corydine.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P24941 Gene ID: 1017.0 Gene Symbol: CDK2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20097066 |
|||
Target ID: P08684 Gene ID: 1576.0 Gene Symbol: CYP3A4 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20851588 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2290126 |
Primary | Unknown Approved UseUnknown |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:06:32 GMT 2023
by
admin
on
Sat Dec 16 08:06:32 GMT 2023
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Record UNII |
1O1D15OP5R
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Record Status |
Validated (UNII)
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Record Version |
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m3803
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