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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H23NO4
Molecular Weight 341.4009
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CORYDINE

SMILES

[H][C@]12CC3=C(C(OC)=C(OC)C=C3)C4=C1C(CCN2C)=CC(OC)=C4O

InChI

InChIKey=IDQUPXZJURZAGF-ZDUSSCGKSA-N
InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H23NO4
Molecular Weight 341.4009
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Corydine is a naturally occurring compound which can be extracted from plants such as Chelidonium majus, Corydalis marschalliana, C. bulbosa, C slivenensis, Glaucium grandiflorum. Corydine has shown some efficacy as an anti-cancer compound in several cell models and was examined along with related compounds from Stephania dinklagei for antiprotozoal activities. (+)- and (-)- Corydine were tested as neuromuscular blocking agents were it was found that there was a modest preference for (+)-corydine.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P24941
Gene ID: 1017.0
Gene Symbol: CDK2
Target Organism: Homo sapiens (Human)
Target ID: P08684
Gene ID: 1576.0
Gene Symbol: CYP3A4
Target Organism: Homo sapiens (Human)
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Selective ther cleavage in the aporphine series. Conversion of (S)-bulbocapnine into (S)-corytuberine and (S)-corydine methyl ether.
1976 Nov 3
Alkaloids from Corydalis bulbosa.
1981 Sep
Alkaloids of Corydalis slivenensis.
1982 Mar
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:06:32 GMT 2023
Edited
by admin
on Sat Dec 16 08:06:32 GMT 2023
Record UNII
1O1D15OP5R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CORYDINE
MI  
Common Name English
D-CORYDINE
Common Name English
(6AS)-5,6,6A,7-TETRAHYDRO-2,10,11-TRIMETHOXY-6-METHYL-4H-DIBENZO(DE,G)QUINOLIN-1-OL
Systematic Name English
(S)-(+)-CORYDINE
Common Name English
GLAUCENTRINE
Common Name English
(+)-CORYDINE
Common Name English
CORYDINE [MI]
Common Name English
CORYTUBERINE METHYL ETHER [MI]
Common Name English
GLAUCENTRIN
Common Name English
O11-METHYLCORYTUBERINE
Common Name English
4H-DIBENZO(DE,G)QUINOLIN-1-OL, 5,6,6A,7-TETRAHYDRO-2,10,11-TRIMETHOXY-6-METHYL-, (6AS)-
Systematic Name English
Code System Code Type Description
DAILYMED
1O1D15OP5R
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY
RXCUI
2593178
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID00963883
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY
FDA UNII
1O1D15OP5R
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY
CAS
476-69-7
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY
MERCK INDEX
m3803
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY Merck Index
MERCK INDEX
m3807
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY Merck Index
PUBCHEM
10153
Created by admin on Sat Dec 16 08:06:32 GMT 2023 , Edited by admin on Sat Dec 16 08:06:32 GMT 2023
PRIMARY