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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H23NO4
Molecular Weight 341.4009
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CORYDINE

SMILES

COC1=CC2=C3[C@H](CC4=C(C(OC)=C(OC)C=C4)C3=C1O)N(C)CC2

InChI

InChIKey=IDQUPXZJURZAGF-ZDUSSCGKSA-N
InChI=1S/C20H23NO4/c1-21-8-7-12-10-15(24-3)19(22)18-16(12)13(21)9-11-5-6-14(23-2)20(25-4)17(11)18/h5-6,10,13,22H,7-9H2,1-4H3/t13-/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H23NO4
Molecular Weight 341.4009
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Corydine is a naturally occurring compound which can be extracted from plants such as Chelidonium majus, Corydalis marschalliana, C. bulbosa, C slivenensis, Glaucium grandiflorum. Corydine has shown some efficacy as an anti-cancer compound in several cell models and was examined along with related compounds from Stephania dinklagei for antiprotozoal activities. (+)- and (-)- Corydine were tested as neuromuscular blocking agents were it was found that there was a modest preference for (+)-corydine.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
1O1D15OP5R
Record Status Validated (UNII)
Record Version