PHENICARBAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9N3O
Molecular Weight	151.1659
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)NNC1=CC=CC=C1

InChI

InChIKey=AVKHCKXGKPAGEI-UHFFFAOYSA-N

InChI=1S/C7H9N3O/c8-7(11)10-9-6-4-2-1-3-5-6/h1-5,9H,(H3,8,10,11)

HIDE SMILES / InChI

Molecular Formula	C7H9N3O
Molecular Weight	151.1659
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.inchem.org/documents/iarc/vol12/phenicarbazide.html | https://www.ncbi.nlm.nih.gov/pubmed/15442328 | https://www.ncbi.nlm.nih.gov/pubmed/4220815

Phenicarbazide, also known as phenylsemicarbazide, is an antipyretic compound. It was shown, that phenicarbazide can cause hemolytic anemia in human and it was carcinogenic in mice.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
[Acute hemolytic anemia in infants induced by administration of phenylsemicarbazide].	1950	14790850
[Phenylsemicarbazide poisoning: hemolytic anemia with hepatitis: 2 cases].	1950	14790851
[Acute hemolytic anemia caused in infants by the administration of large doses of phenylsemicarbazide].	1950 May 30	15442328
[A case of prolonged phenylsemicarbazide poisoning in an adult; comatose form].	1953 Jun 12-19	13082415
[2 cases of acute hemolytic anemia following intake of phenylsemicarbazide. Remarks on poikilocytosis and review of literature].	1965 May-Jun	4220815

Patents

Sample Use Guides

In Vivo Use Guide

hemolytic anemia in human

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:40:49 GMT 2023` Edited by `admin` on `Fri Dec 15 15:40:49 GMT 2023`
Record UNII	1LR2578324
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENICARBAZIDE

Official Name

English

NSC-2763

Code

English

PHENICARBAZIDE [MART.]

Common Name

English

1-PHENYLSEMICARBAZIDE

Systematic Name

English

phenicarbazide [INN]

Common Name

English

PHENICARBAZIDE [IARC]

Common Name

English

Phenicarbazide [WHO-DD]

Common Name

English

PHENICARBAZIDE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2356