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Details

Stereochemistry ACHIRAL
Molecular Formula 2Fe.3O
Molecular Weight 159.688
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC OXIDE RED

SMILES

[O--].[O--].[O--].[Fe+3].[Fe+3]

InChI

InChIKey=LIKBJVNGSGBSGK-UHFFFAOYSA-N
InChI=1S/2Fe.3O/q2*+3;3*-2

HIDE SMILES / InChI
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Monsanto Chemicals
40
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1468
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1447
Chelating Agent
139
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8583
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8583
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
Approved
8583
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
Phosphorus recovery from biogas slurry by ultrasound/H2O2 digestion coupled with HFO/biochar adsorption process.
2017-02
Superior electrochemical performance of N-doped nanocrystalline FeF3/C with a single-step solid-state process.
2016-10-04
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015-11-03
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014-08-26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014-05
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013-04
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011-06
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010-12-07
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007-07-18
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007-02
New phosphate binding agents: ferric compounds.
1999-06
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996-12
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Contact dermatitis to yellow iron oxide.
1985-08
Biological availability of iron supplements for rats, chicks and humans.
1976-02
The absorption of iron as supplements in infant cereal and infant formulas.
1975-05
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973-10
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972-01
[Effects of ferric fluoride compounds on dental enamel].
1954-11-15
Patents

Patents

20090216060
40
6258758
40
US 5206265 A
40
US2385188
40
US4364871
40
US6881255
40
US6903235
40
US7198668
40

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:59:24 GMT 2025
Edited
by admin
on Mon Mar 31 17:59:24 GMT 2025
Record UNII
1K09F3G675
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
FERRIC OXIDE RED
II  
Common Name English
CI 77491
INCI  
INCI  
Preferred Name English
HEMATITE
INCI  
INCI  
Preferred Name English
IRON OXIDES
VANDF  
INCI  
Preferred Name English
DAI COUNTRY RED STONE
Common Name English
FERRIC OXIDE RED-BROWN
Common Name English
FERRIC OXIDE RED 30 [II]
Common Name English
BLOOD STONE
Common Name English
INS NO.172(II)
Common Name English
STONE RED
Common Name English
ANHYDROUS FERRIC OXIDE
Common Name English
PIGMENT BROWN 7
Common Name English
FERRIC OXIDE (ANHYDROUS) [NF]
Common Name English
CI (1975) NO. 77491
Common Name English
IRON OXIDE RED
Common Name English
IRON(III) OXIDE (E 172)
Common Name English
HAEMATITUM
CHP  
Common Name English
COSMETIC RED OXIDE
Common Name English
RED IRON OXIDE R 1599D
Code English
IRON OXIDES [VANDF]
Common Name English
Hematite [WHO-DD]
Common Name English
RED FERRIC OXIDE
Common Name English
IRON OXIDE, RED
Common Name English
INS-172(II)
Common Name English
IRON OXIDE
Common Name English
RED OCHRE
Common Name English
ANHYDROUS IRON (III) OXIDE
Common Name English
IRON OXIDE (E172)
Common Name English
FERRIC OXIDE RED [GREEN BOOK]
Common Name English
E-172(II)
Common Name English
PIGMENT RED 101
Common Name English
IRON OXIDE, SYNTHETIC
Common Name English
FERRIC OXIDE [II]
Common Name English
DAI ZHE HI
Common Name English
INDIAN RED
Common Name English
IRON(III) OXIDE
Common Name English
CALAMINE COMPONENT FERRIC OXIDE RED
Common Name English
ZHESHI
Common Name English
RUBIGO
Common Name English
PIGMENT BROWN 6
Common Name English
IRON OXIDE REDDISH-BROWN
Common Name English
OCHERUM RUBRUM
Common Name English
JEWELER'S ROUGE
Common Name English
C.I. PIGMENT RED 101
Common Name English
RED IRON OXIDE
Common Name English
COLCOTHAR
Common Name English
FERRIC OXIDE
II   MI   VANDF  
Common Name English
C.I. PIGMENT RED 102
Common Name English
FERRIC OXIDE, RED
Common Name English
IRON OXIDE (FE2O3)
Common Name English
E 172 RED
Code English
IRON OXIDE, RED (172(II))
Common Name English
FERRIC OXIDE [MI]
Common Name English
DIIRON TRIOXIDE
Common Name English
HAEMATITUM [CHP]
Common Name English
NATURAL RED OXIDE
Common Name English
FERRIC OXIDE [IARC]
Common Name English
CI PIGMENT RED 101 AND 102
Common Name English
C.I. 77491
Common Name English
IRON TRIOXIDE
Common Name English
FERRIC OXIDE,RED [VANDF]
Common Name English
MAPICO RED
Common Name English
FERRIC OXIDE RED 30
II  
Common Name English
FERRIC OXIDE [VANDF]
Common Name English
FERRIC OXIDE RED [II]
Common Name English
Classification Tree Code System Code
WHO-ATC B03AD04
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
CFR 21 CFR 186.1300
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
DSLD 3326 (Number of products:1)
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-172(II)
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
CFR 21 CFR 176.170
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
JECFA EVALUATION INS-172(II)
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
WHO-ATC V08CB03
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
EPA PESTICIDE CODE 100172
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
CFR 21 CFR 186.1374
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
NCI_THESAURUS C461
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
Code System Code Type Description
HSDB
452
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
RXCUI
1310572
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY RxNorm
EPA CompTox
DTXSID0029632
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
PUBCHEM
14833
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
CHEBI
50819
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
WIKIPEDIA
IRON(III) OXIDE
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
MERCK INDEX
m5325
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY Merck Index
CAS
1317-60-8
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
CONCEPT Industrial Aid
CAS
1309-37-1
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
CAS
1332-37-2
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
ALTERNATIVE
SMS_ID
100000087133
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
ECHA (EC/EINECS)
215-168-2
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
CHEBI
50818
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
DRUG CENTRAL
4443
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
ECHA (EC/EINECS)
215-570-8
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
ALTERNATIVE
EVMPD
SUB16058MIG
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
CAS
12002-17-4
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
ALTERNATIVE
DAILYMED
1K09F3G675
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
MERCK INDEX
m5362
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY Merck Index
FDA UNII
1K09F3G675
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
EVMPD
SUB23080
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
DRUG BANK
DB11576
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
CHEBI
50820
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
ECHA (EC/EINECS)
215-275-4
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C75672
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
EVMPD
SUB168473
Created by admin on Mon Mar 31 17:59:24 GMT 2025 , Edited by admin on Mon Mar 31 17:59:24 GMT 2025
PRIMARY
Related Record Type Details
FERUMOXTRAN-10
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
Structure of FERRIC CATION
ACTIVE MOIETY
NIH
NCATS
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