| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H24O |
| Molecular Weight | 220.3505 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C\C(CO)=C\CC[C@]1(C)[C@H]2CC[C@H](C2)C1=C
InChI
InChIKey=OJYKYCDSGQGTRJ-GQYWAMEOSA-N
InChI=1S/C15H24O/c1-11(10-16)5-4-8-15(3)12(2)13-6-7-14(15)9-13/h5,13-14,16H,2,4,6-10H2,1,3H3/b11-5-/t13-,14+,15+/m1/s1
| Molecular Formula | C15H24O |
| Molecular Weight | 220.3505 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
(Z)-β-Santalol is a key component of sandalwood oil, which when purified, can be used to treat the common cold, bronchitis, fever, and urinary tract infections, and it has also been shown to have anti-inflammatory properties and cause autophagy in proliferating keratinocytes. β-Santalol has antiviral and anticancer activities. As of 2002, about 60 tons of sandalwood oil are produced annually by steam distillation of the heartwood of Santalum album.
Originator
Approval Year
PubMed
Patents
Sample Use Guides
Female athymic nude mice were treated with topical application of 5 μL (days 0−2), 10 μL (days 3−4), or 20 μL (days 7−11 and 14−18) of a 50:50 solution of East Indian sandalwood oil (EISO)/DMSO. The β-santalol content of EISO was 20.73% as determined by GC/FID analysis
Route of Administration:
Topical
The MICs of the (Z)-β-Santalol and antibiotics were determined by the 2-fold plate-dilution method using Mueller-Hinton medium supplemented with 5% sheep blood (Nippon Biotest Laboratories Inc.). Bacterial suspensions equivalent to a 2.0 MacFarland standard (containing 1 x 10^8 CFU/mL) were prepared in saline from a 72 h subculture from a blood agar plate, and the bacteria (5 mkL per spot) were applied with an inoculator onto the surfaces of 10 mm agar layers. The plates were read after 4 days’ incubation at 37 °C under the micro-aerophilic conditions with humidity.