VEROFYLLINE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H18N4O2
Molecular Weight	250.2969
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(C)CN1C2=C(N=C(C)N2)C(=O)N(C)C1=O

InChI

InChIKey=MTBUJUHRXVGLEF-UHFFFAOYSA-N

InChI=1S/C12H18N4O2/c1-5-7(2)6-16-10-9(13-8(3)14-10)11(17)15(4)12(16)18/h7H,5-6H2,1-4H3,(H,13,14)

HIDE SMILES / InChI

Molecular Formula	C12H18N4O2
Molecular Weight	250.2969
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6388955

Verofylline is a derivative of naturally occurring purine base xanthine. Verofylline acts as a long-acting bronchodilator. In animals, the drug has stronger bronchodilator activity but weaker chronotropic and inotropic activity than theophylline. A clinical trial of verofylline in patients with asthma has shown only weak activity.

Approval Year

PubMed

Title	Date	PubMed
Verofylline, a methylxanthine bronchodilator, in asthma.	1984-12	6388955

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:29:24 GMT 2025` Edited by `admin` on `Mon Mar 31 19:29:24 GMT 2025`
Record UNII	1J8O1GT31U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CK-0383

Preferred Name

English

VEROFYLLINE

Official Name

English

verofylline [INN]

Common Name

English

VEROFYLLINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C319