LY-3200882

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H29N5O3
Molecular Weight	435.5188
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(O)C1=CC(NC2=CC(OC3=CN(N=C3C4CCOCC4)C5CC5)=CC=N2)=CC=N1

InChI

InChIKey=PNPFMWIDAKQFPY-UHFFFAOYSA-N

InChI=1S/C24H29N5O3/c1-24(2,30)21-13-17(5-9-25-21)27-22-14-19(6-10-26-22)32-20-15-29(18-3-4-18)28-23(20)16-7-11-31-12-8-16/h5-6,9-10,13-16,18,30H,3-4,7-8,11-12H2,1-2H3,(H,25,26,27)

HIDE SMILES / InChI

Molecular Formula	C24H29N5O3
Molecular Weight	435.5188
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
TGF-beta receptor type-1 8 Target ID: P36897 Gene ID: 7046.0 Gene Symbol: TGFBR1 Target Organism: Homo sapiens (Human) Sources: https://cancerres.aacrjournals.org/content/77/13_Supplement/955	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:37:30 GMT 2023` Edited by `admin` on `Sat Dec 16 11:37:30 GMT 2023`
Record UNII	19HY34R6UN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LY-3200882

Code

English

4-((4-((1-CYCLOPROPYL-3-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOL-4-YL)OXY)-2-PYRIDINYL)AMINO)-.ALPHA.,.ALPHA.-DIMETHYL-2-PYRIDINEMETHANOL

Systematic Name

English

LY3200882

Code

English

LY 3200882 [WHO-DD]

Common Name

English

2-PYRIDINEMETHANOL, 4-((4-((1-CYCLOPROPYL-3-(TETRAHYDRO-2H-PYRAN-4-YL)-1H-PYRAZOL-4-YL)OXY)-2-PYRIDINYL)AMINO)-.ALPHA.,.ALPHA.-DIMETHYL-

Systematic Name

English

Code System Code Type Description

PUBCHEM

121249291