SEGANSERIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C29H27F2N3O
Molecular Weight	471.541
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=C(CCN2CCC(CC2)=C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C(=O)N5C=CC=CC5=N1

InChI

InChIKey=ZGUPMFYFHHSNFK-UHFFFAOYSA-N

InChI=1S/C29H27F2N3O/c1-20-26(29(35)34-16-3-2-4-27(34)32-20)15-19-33-17-13-23(14-18-33)28(21-5-9-24(30)10-6-21)22-7-11-25(31)12-8-22/h2-12,16H,13-15,17-19H2,1H3

HIDE SMILES / InChI

Molecular Formula	C29H27F2N3O
Molecular Weight	471.541
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8853256

Seganserin was developed as a specific serotonin 5HT2 receptor antagonist. It was tested neuropharmacologically in thioacetamide-induced acute liver failure in rats. Obtained results have shown that seganserin had no effect in encephalopathic rats.

Approval Year

PubMed

Title	Date	PubMed
Effect of 5-HT1A and 5-HT2A/2C receptor modulation on neuroleptic-induced vacuous chewing movements.	2001 Sep 28	11779040

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:41:56 GMT 2023` Edited by `admin` on `Fri Dec 15 15:41:56 GMT 2023`
Record UNII	197HL4EZCC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SEGANSERIN

Official Name

English

seganserin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66885