CLOPAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H20ClN3O3S
Molecular Weight	345.845
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H]1CCC[C@@H](C)N1NC(=O)C2=CC=C(Cl)C(=C2)S(N)(=O)=O

InChI

InChIKey=LBXHRAWDUMTPSE-AOOOYVTPSA-N

InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

HIDE SMILES / InChI

Molecular Formula	C14H20ClN3O3S
Molecular Weight	345.845
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: http://www.healthplus24.com/drugs/clopamide.aspx

Clopamide is a thiazide diuretic which helps in removing fluid from the body. Clopamide is used in treatment of hypertension and edema.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Hypertension 567 Sources: http://www.healthplus24.com/drugs/clopamide.aspx	Primary		Approved 8429	BRINALDIX Approved Use Clopamide is used in treatment of hypertension and excessive fluid retention as in cardiac failure, cirrhosis, chronic renal failure, Nephrotic syndrome, Cushing’s disease.
Edema 22 Sources: http://www.healthplus24.com/drugs/clopamide.aspx	Primary		Approved 8429	BRINALDIX Approved Use Clopamide is used in treatment of hypertension and excessive fluid retention as in cardiac failure, cirrhosis, chronic renal failure, Nephrotic syndrome, Cushing’s disease.

PubMed

Title	Date	PubMed
Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation.	2005 Aug	16044110
Influence of atypical neuroleptics on executive functioning in patients with schizophrenia: a randomized, double-blind comparison of olanzapine vs. clozapine.	2006 Apr	16174427
High-speed gas chromatography in doping control: fast-GC and fast-GC/MS determination of beta-adrenoceptor ligands and diuretics.	2006 Dec	17305237
Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysis.	2006 Dec 1	17027009
[Simultaneous determination of five illegal drugs in weight control foods with solid phase extraction-high performance liquid chromatography].	2010 Sep	21302462

Sample Use Guides

In Vivo Use Guide

Take clopamide on empty stomach 15 min before meals with one full glass of water.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:45:44 GMT 2023` Edited by `admin` on `Sat Dec 16 17:45:44 GMT 2023`
Record UNII	17S83WON0I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLOPAMIDE

Official Name

English

CLOPAMIDE [MART.]

Common Name

English

BENZAMIDE, 3-(AMINOSULFONYL)-4-CHLORO-N-(2,6-DIMETHYL-1-PIPERIDINYL)-, CIS-

Common Name

English

clopamide [INN]

Common Name

English

CLOPAMIDE [MI]

Common Name

English

CLOPAMIDE [EP MONOGRAPH]

Common Name

English

4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide

Systematic Name

English

DT-327

Code

English

Clopamide [WHO-DD]

Common Name

English

AQUEX

Brand Name

English

CLOPAMIDE [EP IMPURITY]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C49185