TROPATEPINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H23NS.ClH
Molecular Weight	369.951
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CN1[C@H]2CC[C@@H]1C\C(C2)=C3/C4=CC=CC=C4SCC5=C3C=CC=C5

InChI

InChIKey=LVASURLUIYTDHW-ZCTOARNVSA-N

InChI=1S/C22H23NS.ClH/c1-23-17-10-11-18(23)13-16(12-17)22-19-7-3-2-6-15(19)14-24-21-9-5-4-8-20(21)22;/h2-9,17-18H,10-14H2,1H3;1H/b22-16-;/t17-,18+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	C22H23NS
Molecular Weight	333.49
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2769291 | https://www.onmeda.fr/medicament/lepticur-93140500.html

Tropatepine is an anticholinergic drug. Intramuscular injections of tropatepine are used to counteract the extrapyramidal effects of neuroleptic drugs and for the treatment of Parkinson's disease. The drug is marketed in Europe under tradename Lepticur.

Approval Year

PubMed

Title	Date	PubMed
Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease.	1989-07	2769291

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:40:50 GMT 2025` Edited by `admin` on `Mon Mar 31 19:40:50 GMT 2025`
Record UNII	17N1U39U3Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SD-1248-17

Preferred Name

English

TROPATEPINE HYDROCHLORIDE

Common Name

English

TROPATEPINE HYDROCHLORIDE [MART.]

Common Name

English

Tropatepine hydrochloride [WHO-DD]

Common Name

English

TROPATEPINE HCL

Common Name

English

3-(DIBENZO(B,E)THIEPIN-11(6H)-YLIDENE)TROPANE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

RXCUI

236190