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Details

Stereochemistry ACHIRAL
Molecular Formula C21H23ClN4O2.ClH
Molecular Weight 435.347
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLOPERIDONE HYDROCHLORIDE

SMILES

Cl.ClC1=CC=CC(=C1)N2CCN(CCCN3C(=O)NC4=C(C=CC=C4)C3=O)CC2

InChI

InChIKey=QUGOVTRSGWYKSQ-UHFFFAOYSA-N
InChI=1S/C21H23ClN4O2.ClH/c22-16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-4-10-26-20(27)18-7-1-2-8-19(18)23-21(26)28;/h1-3,5-8,15H,4,9-14H2,(H,23,28);1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H23ClN4O2
Molecular Weight 398.886
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Cloperidone is a quinazolinedione derivative with sedative and antihypertensive properties. Cloperidone was discovered in 1965 by Miles Laboratories. The activity of the compound was demonstrated by behavioral observations in dogs and cats, by rotarod and activity cage experiments in mice and in other models.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
New sedative and hypotensive 3-substituted 2,4(1H,3H)-quinazolinediones.
1965 Nov
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:30 GMT 2023
Edited
by admin
on Fri Dec 15 15:00:30 GMT 2023
Record UNII
17682058OP
Record Status Validated (UNII)
Record Version
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Name Type Language
CLOPERIDONE HYDROCHLORIDE
USAN  
USAN  
Official Name English
CLOPERIDONE HYDROCHLORIDE [USAN]
Common Name English
CLOPERIDONE HCL
Common Name English
MA 1337
Code English
NSC-198100
Code English
2,4(1H,3H)-QUINAZOLINEDIONE, 3-(3-(4-(3-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-, MONOHYDROCHLORIDE
Common Name English
3-(3-(4-(M-CHLOROPHENYL)-1-PIPERAZINYL)PROPYL)-2,4-(1H,3H)-QUINAZOLINEDIONE MONOHYDROCHLORIDE
Systematic Name English
MA-1337
Code English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID20200500
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110792
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
FDA UNII
17682058OP
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
NSC
198100
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
PUBCHEM
10674
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
NCI_THESAURUS
C80665
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
CAS
525-26-8
Created by admin on Fri Dec 15 15:00:30 GMT 2023 , Edited by admin on Fri Dec 15 15:00:30 GMT 2023
PRIMARY
Related Record Type Details
Structure of CLOPERIDONE
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