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Details

Stereochemistry ACHIRAL
Molecular Formula C18H13O4S.Na
Molecular Weight 348.348
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIFURAC SODIUM ANHYDROUS

SMILES

[Na+].CSC1=CC=C(C=C1)C(=O)C2=CC(CC([O-])=O)=CC3=C2OC=C3

InChI

InChIKey=AMHWUAATYNXBDN-UHFFFAOYSA-M
InChI=1S/C18H14O4S.Na/c1-23-14-4-2-12(3-5-14)17(21)15-9-11(10-16(19)20)8-13-6-7-22-18(13)15;/h2-9H,10H2,1H3,(H,19,20);/q;+1/p-1

HIDE SMILES / InChI
Molecular Formula C18H13O4S
Molecular Weight 325.358
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tifurac is a benzofuranacetic acid derivative patented by Syntex, Inc. as an analgesic, anti-inflammatory, and antipyretic agent. In preclinical models, Tifurac can exert anti-inflammatory and analgesic activity in rat paw edema assay and mouse writhing assay.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Analgetic and antiinflammatory 7-aroylbenzofuran-5-ylacetic acids and 7-aroylbenzothiophene-5-ylacetic acids.
1986 Nov
Synthesis and biological evaluation of omega-(N,N,N-trialkylammonium)alkyl esters and thioesters of carboxylic acid nonsteroidal antiinflammatory agents.
1989 Oct
Patents

Patents

EP132130
3
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:45:05 GMT 2023
Edited
by admin
on Sat Dec 16 05:45:05 GMT 2023
Record UNII
16MZ0551Z2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TIFURAC SODIUM ANHYDROUS
Common Name English
5-BENZOFURANACETIC ACID, 7-(4-(METHYLTHIO)BENZOYL)-, SODIUM SALT (1:1)
Common Name English
SODIUM (7-(4-METHYLTHIOBENZOYL)-5-BENZOFURAN)ACETATE
Common Name English
Code System Code Type Description
PUBCHEM
23676445
Created by admin on Sat Dec 16 05:45:05 GMT 2023 , Edited by admin on Sat Dec 16 05:45:05 GMT 2023
PRIMARY
FDA UNII
16MZ0551Z2
Created by admin on Sat Dec 16 05:45:05 GMT 2023 , Edited by admin on Sat Dec 16 05:45:05 GMT 2023
PRIMARY
CAS
514172-76-0
Created by admin on Sat Dec 16 05:45:05 GMT 2023 , Edited by admin on Sat Dec 16 05:45:05 GMT 2023
PRIMARY
Related Record Type Details
Structure of TIFURAC SODIUM
SOLVATE->ANHYDROUS
Related Record Type Details
Structure of TIFURAC
ACTIVE MOIETY
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